儿童空气污染暴露与CC16相关研究进展

doi:10.11852/zgetbjzz2017-25-02-12

中国儿童保健杂志 ›› 2017, Vol. 25 ›› Issue (2): 151-153.DOI: 10.11852/zgetbjzz2017-25-02-12

儿童空气污染暴露与CC16相关研究进展

史航¹,朱运²,吕雪峰³,何钦成⁴,马亚楠⁴

1 中国医科大学第一临床学院,辽宁沈阳 110001;
2 中国医科大学口腔医学院,辽宁沈阳 110001;
3 辽宁省大气污染防治管理中心,辽宁沈阳 110161;
4 中国医科大学公共卫生学院卫生统计教研室,辽宁沈阳 110122

收稿日期:2016-05-10 发布日期:2017-02-10 出版日期:2017-02-10
通讯作者: 马亚楠,E-mailynma@cmu.edu.cn
作者简介:史航(1994-),女,辽宁人,在读研究生,主要研究方向为生物标志物研究。
基金资助:
国家自然科学基金(81302405);中华环境保护基金项目(CEPF2010-123-1-3);沈阳市科学技术项目计划项目(F13-220-9-34);辽宁省“大学生创新创业训练计划项目”(2015066)

Advances in research on children's exposure to air pollution and CC16

SHI Hang¹,ZHU Yun²,LV Xue-feng³,HE Qin-cheng⁴,MA Ya-nan⁴

1 The First Clinical College of China Medical University,Shenyang,Liaoning 110001,China;
2 College of Dental Medicine,China Medical University,Shenyang,Liaoning 110001,China;
3 Liaoning Province Atmospheric Pollution Prevention Management Center,Shenyang,Liaoning 110161,China;
4 Department of Statistics,School of Public Health,China Medical University,Shenyang,Liaoning 110122,China

Received:2016-05-10 Online:2017-02-10 Published:2017-02-10
Contact: MA Ya-nan,E-mail:ynma@cmu.edu.cn

摘要/Abstract

摘要： 随着现代社会的迅猛发展,空气污染加剧,引起了一系列呼吸系统疾病,受到人们广泛关注。肺部疾病的生物标记物Clara细胞分泌蛋白(CC16)主要是由分布在呼吸道的Clara细胞分泌产生,有保护气道的作用。近年来研究表明室内外空气污染暴露可能会影响CC16水平,但具体机制尚不完全清楚。本文从室内外空气污染暴露与儿童CC16关系以及空气污染影响CC16的机制等方面进行综述。

关键词: 室内外空气污染, CC16, 生物学特性, 变化机制

Abstract: With the rapid development of modern society,a series of respiratory diseases caused by air pollution have been widely concerned.Clara cell secretory protein (CC16),a biomarker of lung disease,is mainly produced by the secretion of Clara cells in the respiratory tract.In recent years,the study show that indoor and outdoor air pollution exposure may affect the level of CC16,but the specific mechanism is not completely clear.In this paper,the relationship between indoor and outdoor air pollution exposure and children's CC16 and the mechanism of the effect of air pollution on CC16 are reviewed in detail.

Key words: indoor and outdoor air pollution, CC16, biological characteristics, mechanism of change

中图分类号:

R179

史航,朱运,吕雪峰,何钦成,马亚楠. 儿童空气污染暴露与CC16相关研究进展[J]. 中国儿童保健杂志, 2017, 25(2): 151-153.

SHI Hang,ZHU Yun,LV Xue-feng,HE Qin-cheng,MA Ya-nan. Advances in research on children's exposure to air pollution and CC16[J]. journal1, 2017, 25(2): 151-153.

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儿童空气污染暴露与CC16相关研究进展

Advances in research on children's exposure to air pollution and CC16

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