中国儿童保健杂志 ›› 2020, Vol. 28 ›› Issue (2): 211-214.DOI: 10.11852/zgetbjzz2019-0463

• 经验交流 • 上一篇    下一篇

抚顺地区6 766例0~14岁儿童血清维生素A水平调查研究

许颖, 苏艳琦, 郎会利, 张玉伟   

  1. 辽宁省健康产业集团抚矿总医院(中国医科大学第七临床学院),辽宁 抚顺 113008
  • 收稿日期:2019-04-07 出版日期:2020-02-10 发布日期:2020-02-10
  • 作者简介:许颖(1985-),女,主治医师,硕士学位,主要研究方向为儿科疾病的诊治。
  • 基金资助:
    国家卫生计生委医药卫生科技发展研究中心项目(W2016EWQT44)

Investigation on vitamin A level in 6 766 children aged 0 to 14 years in Fushun

XU Ying, SU Yan-qi, LANG Hui-li, ZHANG Yu-wei   

  1. Department of Pediatrics,Fushun Mining Bureau General Hospital,Fushun,Liaoning 113008,China
  • Received:2019-04-07 Online:2020-02-10 Published:2020-02-10

摘要: 目的 调查抚顺地区0~14岁儿童血清维生素A水平状况,为本地区儿童合理补充维生素A提供依据,为临床工作提供参考。方法 对2015年1月-2018年12月在辽健集团抚矿总医院儿科保健门诊健康体检的6 766例0~14岁儿童采用高效液相色谱法测定血清维生素A水平。结果 亚临床维生素A缺乏检出率为17.85%(1 208/6 766),可疑亚临床维生素A缺乏检出率为43.26%(2 927/6 766)。近四年儿童血清维生素A水平比较差异有统计学意义(P<0.05),2018年可疑亚临床维生素A缺乏检出率为45.3%,亚临床维生素A缺乏检出率为10.5%,已较前明显下降。不同性别儿童血清维生素A水平差异无统计学意义(P>0.05)。不同季节检测儿童血清维生素A水平差异有统计学意义(P<0.05),秋季儿童血清维生素A水平高于其他季节。不同年龄组儿童血清维生素A水平差异有统计学意义(P<0.05)。随年龄增长血清维生素A缺乏检出率逐渐下降,≤1月组及1~6月组血清维生素A水平明显低于其他年龄组,6~14岁组儿童血清维生素A平均水平在正常范围。结论 抚顺地区0~14岁儿童血清维生素A水平普遍偏低,0~6月龄婴儿的维生素A营养状况问题较为严重。应注意调整膳食结构,合理补充维生素A,预防维生素A缺乏症的发生。

关键词: 维生素A缺乏, 临床维生素A缺乏, 儿童

Abstract: Objective To investigate the serum level of vitamin A in children aged 0 to 14 years in Fushun city,so as to provide reasonable scientific basis for vitamin A supplementation and reference for clinical diagnosis and treatment. Methods Totally 6 766 healthy children aged 0 to 14 years,who took physical examination in Fushun Mining Bureau General Hospital,were recruited in this study from January,2015 to December,2018.Serum vitamin A level was tested by high performance liquid chromatography. Results The detection rates of subclinical vitamin A deficiency and suspicious subclinical vitamin A deficiency were 17.85% (1 208/6 766) and 43.26%(2 927/6 766).There was significantly difference on serum vitamin A level from 2015 to 2018(P<0.05).The detection rates of suspicious subclinical vitamin A deficiency and subclinical vitamin A deficiency were 45.3% and 10.5%,respectively,significantly lower than before.There was no significant difference on serum vitamin A level between boys and girls (P>0.05).But significant difference existed among different seasons(P<0.05),and vitamin A level was highest in autumn.There was also significant difference on serum level of vitamin A among different age groups (P<0.05).Serum vitamin A deficiency rate gradually decreased with the increasing of age.Serum level of vitamin A in children under 1 month old and aged 1 to 6 months was significantly lower than that in other age groups.However,vitamin A level of children aged 6 to 14 years was in the normal range. Conclusions Serum vitamin A level of children aged 0 to 14 years in Fushun is still lower,especially in infants aged 0 to 6 months.Thus,more attention should be paid to the dietary structure adjustment and rational vitamin A supplementation in order to prevent vitamin A deficiency.

Key words: vitamin A deficiency, subclinical vitamin A defieiency, children

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