中国儿童保健杂志 ›› 2021, Vol. 29 ›› Issue (4): 393-396.DOI: 10.11852/zgetbjzz2020-1036

• 综述 • 上一篇    下一篇

维生素D与脑发育相关研究进展

秦莹, 仰曙芬   

  1. 哈尔滨医科大学附属第二医院儿科,黑龙江 哈尔滨 150081
  • 收稿日期:2020-06-02 修回日期:2020-11-12 出版日期:2021-04-10 发布日期:2021-04-27
  • 通讯作者: 仰曙芬,E-mail:yangshufen513@126.com
  • 作者简介:秦莹(1993-),女,黑龙江人,硕士研究生,主要研究方向为儿童保健。
  • 基金资助:
    黑龙江省社会发展攻关项目(07040002004)

Research progressin vitamin D and brain development

QIN Ying, YANG Shu-fen   

  1. Department of Pediatrics, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China
  • Received:2020-06-02 Revised:2020-11-12 Online:2021-04-10 Published:2021-04-27
  • Contact: YANG Shu-fen,E-mail:yangshufen513@126.com

摘要: 近年来有关维生素D研究进展迅速,其中维生素D与大脑的发育之间的关系日益受到关注。维生素D是一种具有类固醇激素作用的物质,可参与调节细胞増殖、分化及凋亡,大量研究表明,维生素D除了具有促进钙磷吸收、骨骼发育及发挥免疫调节的作用,还可作为一类神经激素影响神经系统的发育和功能,本文将从大脑中的维生素D及维生素D受体、维生素D对脑发育可能的调控作用及维生素D与儿童神经精神障碍疾病的相关性等几方面进行阐述。

关键词: 维生素D, 维生素D受体, 脑发育

Abstract: In recent years, research on vitamin D has been progressing rapidly, and the relationship between vitamin D and brain development has received increasing attention. Vitamin D is a steroid hormone that can participate in the regulation of cell proliferation, differentiation and apoptosis. In addition to promoting calcium and phosphorus absorption, bone development and immune regulation, a large number of studies have shown that vitamin D can also affect nerves as a type of neurohormone for the development and function of the system. This article will focus on the vitamin D and vitamin D receptor (VDR) in the brain, the possible regulation of vitamin D on brain development, and the correlation between vitamin D and neuropsychiatric disorders in children.

Key words: vitamin D, vitamin D receptor, brain development

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