中国六城市46 073例早期儿发育性协调障碍的调查

doi:10.11852/zgetbjzz2021-0080

中国儿童保健杂志 ›› 2021, Vol. 29 ›› Issue (12): 1291-1294.DOI: 10.11852/zgetbjzz2021-0080

中国六城市46 073例早期儿发育性协调障碍的调查

张嘉佳¹, 王磊², 陈桂霞³, 林尧⁴, 花静¹

1.同济大学附属第一妇婴保健院, 上海 201204;
2.扬州大学医学院附属医院扬州市妇幼保健院;
3.厦门大学附属妇女儿童医院;
4.海南省海口市妇幼保健院

收稿日期:2021-01-19 修回日期:2021-04-19 发布日期:2021-12-09
通讯作者: 花静,E-mail:jinghua@tongji.edu.cn
作者简介:张嘉佳(1997-), 女,硕士研究生在读,主要研究方向为儿童保健。
基金资助:
国家自然科学基金委员会面上项目(81673179); 上海市卫生健康委老龄化和妇儿健康研究专项(2020YJZX0213); 上海市申康医院三年行动计划重大临床研究项目(SHDC2020CR1047B-003)

Survey on early infant developmental coordination disorder in 46 073 cases in six cities of China

ZHANG Jia-jia^*, WANG Lei, CHEN Gui-xia, LIN Yao, HUA Jing

^*Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China

Received:2021-01-19 Revised:2021-04-19 Published:2021-12-09
Contact: HUA Jing, E-mail:jinghua@tongji.edu.cn

摘要/Abstract

摘要： 目的分析“早期”(37～38孕周)出生对儿童发育性协调障碍(DCD)的影响,为确定重点干预和预防人群提供线索。方法 2018年4-12月纳入上海、马鞍山、台州、海口、厦门、扬州6个城市670所幼儿园的学龄前儿童共46 073例,用小龄发育性协调障碍问卷进行运动协调能力的评估。结果研究结果显示,与完全足月儿相比,早期儿总的运动协调能力(67.30±8.90 vs.67.50±8.80)、运动控制能力(22.82±3.08 vs.22.89±3.04)及一般协调性(21.95±3.26 vs.22.03±3.21)等均低于完全足月儿(t=2.174、2.201、2.382,P<0.05)。多因素分析显示在控制了性别、年龄、BMI、父母亲教育程度等潜在混杂因素后,早期儿组女童DCD发生风险较完全足月儿女童增加15.7%(OR=1.157,95%CI:1.001~1.340,P<0.05)。结论早期儿可作为DCD早期评估和干预的重点人群,加强早期儿健康管理是“二孩政策”下提高人口素质,节约医疗成本的关键“切入点”之一。

关键词: 发育性协调障碍, 早期儿, 儿童

Abstract: Objective To explore the influence of early-term birth (gestational age of 37 to 38 weeks) on developmental coordination disorder (DCD), so as to provide clues for targeting the population receiving intervention and prevention. Methods A total of 46 073 preschool children from 670 kindergartens in Shanghai, Maanshan, Taizhou, Haikou, Xiamen and Yangzhou were enrolled from April to December 2018.The ability of motor coordination was assessed using Little Developmental Coordination Disorder Questionnaire (Little DCDQ). Results The score of total motor coordination (67.30±8.90 vs.67.50±8.80), motor control (22.82±3.08 vs.22.89±3.04) and general coordination (21.95±3.26 vs.22.03±3.21) in early children were lower than those of completely full term children (t= 2.174, 2.201, 2.382, P<0.05).Multivariate analysis showed that after controlling for potential confounding factors such as sex, age and education level of parents, body mass index(BMI), the risk of DCD in girls with early-term birth was 1.157 times higher than that with full-term birth (OR=1.157,95%CI:1.001-1.340, P<0.05). Conclusions Early-term infants should be attached great importance in early assessment and intervention of DCD.Strengthening the healthcare in early-term children would be one of the key points to promote the quality of population and save the medical expenditure under the "two-child" policy.

Key words: developmental coordination disorder, early term, children

中图分类号:

R174

张嘉佳, 王磊, 陈桂霞, 林尧, 花静. 中国六城市46 073例早期儿发育性协调障碍的调查[J]. 中国儿童保健杂志, 2021, 29(12): 1291-1294.

ZHANG Jia-jia, WANG Lei, CHEN Gui-xia, LIN Yao, HUA Jing. Survey on early infant developmental coordination disorder in 46 073 cases in six cities of China[J]. Chinese Journal of Child Health Care, 2021, 29(12): 1291-1294.

参考文献

[1] Caravale B, Herich L, Zoia S, et al.Risk of developmental coordination disorder in italian very preterm children at school age compared to general population controls[J].Eur J Paediatr Neurol, 2019, 23(2):296-303.
[2] Skranes J.Is developmental coordination disorder in preterm children the motor phenotype of more widespread brain pathology?[J].Acta Paediatr,2019, 108:1559-1561.
[3] Hua J, Sun J, Cao ZJ, et al.Differentiating the cognitive development of early-term births in infants and toddlers:a cross-sectional study in China[J].BMJ Open, 2019, 9(4):e025275.
[4] 崔娓, 戴霄天, 林森然, 等.不同出生胎龄对婴幼儿神经行为能力影响的研究[J].中国儿童保健杂志, 2020, 28(12):5-8.
[5] Ou JJ, Shi LJ, Xun GL, et al.Employment and financial burden of families with preschool children diagnosed with autism spectrum disorders in urban China:results from a descriptive study[J].BMC Psychiatry, 2015, 15:3.
[6] Hua J, Jin H, Gu GX, et al.The influence of Chinese one-child family status on developmental coordination disorder status[J]. Res Dev Disabil, 2014, 35(11):3089-3095.
[7] Hua J, Gu GG, Jiang PQ, et al.The prenatal, perinatal and neonatal risk factors for children's developmental coordination disorder:a population study in mainland China[J]. Res Dev Disabil, 2014, 35(3):619-625.
[8] 耿姗姗, 戴霄天, 王天景, 等.中文版小龄发育性协调障碍问卷信效度的初步研究[J].临床儿科杂志, 2020, 38(12):921-924.
[9] Davis NM, Ford GW, Anderson PJ, et al.Developmental coordination disorder at 8 years of age in a regional cohort of extremely-low-birthweight or very preterm infants[J].Dev Med Child Neurol, 2007, 49(5):325-330.
[10] Dewey D, Thompson DK, Kelly CE et al.Very preterm children at risk for developmental coordination disorder have brain alterations in motor areas[J].Acta Paediatr, 2019, 108(9):1649-1660.
[11] Bolk J, Farooqi A, Hafström M, et al.Developmental coordination disorder and its association with developmental comorbidities at 6.5 years in apparently healthy children born extremely preterm[J]. JAMA Pediatr, 2018, 172(8):765-774.
[12] Zhang X, Zhou M, Yin H, et al.The predictive value of early oral motor assessments for neurodevelopmental outcomes of moderately and late preterm infants[J].Medicine (Baltimore), 2017, 96(50):e9207.
[13] Johnson S, Waheed G, Manktelow BN, et al.Differentiating the preterm phenotype:Distinct profiles of cognitive and behavioral development following late and moderately preterm birth[J].J Pediatr, 2018, 193:85-92.
[14] van Batenburg-Eddes T, de Groot L, Arends L, et al.Does gestational duration within the normal range predict infant neuromotor development?[J].Early Hum Dev, 2008, 84(10):659-665.
[15] Rose O, Blanco E, Martinez SM, et al.Developmental scores at 1 year with increasing gestational age, 37-41 weeks[J].Pediatrics, 2013, 131(5):e1475-1481.
[16] van Eden CG, Uylings HB, van Pelt J.Sex-difference and left-right asymmetries in the prefrontal cortex during postnatal development in the rat[J].Brain Res, 1984, 314(1):146-153.
[17] de Courten-Myers GM.The human cerebral cortex:gender differences in structure and function[J].J Neuropathol Exp Neurol, 1999, 58(3):217-226.

中国六城市46 073例早期儿发育性协调障碍的调查

Survey on early infant developmental coordination disorder in 46 073 cases in six cities of China

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	向伟. 儿童青少年脂质异常血症早期预防与成人期心血管健康[J]. 中国儿童保健杂志, 2023, 31(7): 697-702.
[2]	吴婷, 李斐. 生命早期不利因素与慢性疾病的发生与预防[J]. 中国儿童保健杂志, 2023, 31(7): 703-706.
[3]	刘浩东, 李成, 赵敏, 席波. 儿童期腹型肥胖及其腹型肥胖前期与高尿酸血症的关联研究[J]. 中国儿童保健杂志, 2023, 31(7): 707-712.
[4]	刘敏, 张倩, 杨亭, 陈洁, 陈立, 代英, 贾飞勇, 武丽杰, 郝燕, 李玲, 张婕, 柯晓燕, 衣明纪, 洪琦, 陈津津, 方拴锋, 王益超, 王琦, 金春华, 李廷玉. 全国多中心学龄前儿童血清叶酸现况调查[J]. 中国儿童保健杂志, 2023, 31(7): 713-717.
[5]	霍言言, 刘钟泠, 马玲, 吴丹, 汪秀莲, 仇晓艳, 窦家莹, 任玉倩, 李亦诚, 洪霞, 陈津津. 真实世界2岁以下儿童不同体型匀称度现况及风险因素[J]. 中国儿童保健杂志, 2023, 31(7): 718-723.
[6]	刘慧娟, 宋志霄, 高南南, 张莉, 孙瑾, 乔秀芸, 柯佳媚, 李燕. 2～6岁儿童词汇和语法发展现状及相关因素分析[J]. 中国儿童保健杂志, 2023, 31(7): 724-730.
[7]	李荣, 李年, 吴丹丹, 黄荣, 陈银花. 盐酸哌甲酯缓释片对注意缺陷多动障碍儿童生长的影响[J]. 中国儿童保健杂志, 2023, 31(7): 731-735.
[8]	张超. 早期介入丹佛模式在不同病情程度孤独症谱系障碍儿童康复中的应用研究[J]. 中国儿童保健杂志, 2023, 31(7): 736-740.
[9]	杨钰儒, 王红, 许树红, 曹艳梅, 孟仙, 葛冬梅. 0～14岁儿童骨骼发育与维生素K的关联研究[J]. 中国儿童保健杂志, 2023, 31(7): 746-750.
[10]	叶芝旭, 余福勋. 肠道微生物与儿童呼吸道病毒感染的研究进展[J]. 中国儿童保健杂志, 2023, 31(7): 766-769.
[11]	曹慧, 严双琴, 关宏岩. 亲子互动对儿童早期发展结局的影响[J]. 中国儿童保健杂志, 2023, 31(7): 770-774.
[12]	张容, 吴襄仪, 朱一民, 朱文丽, 《儿童肥胖预防与控制指南》修订委员会. 就餐地点与儿童肥胖的定性循证研究[J]. 中国儿童保健杂志, 2023, 31(7): 775-780.
[13]	李玮玮, 张丹丹, 刘晓鸣, 陈娇, 夏露. 探讨基于互联网技术的长程管理模式在难治性癫痫患儿中的应用研究[J]. 中国儿童保健杂志, 2023, 31(7): 781-784.
[14]	朱丽君, 李彪章, 周嘉雯, 吴柏欣, 李卫东. 1990—2019年中国5岁以下儿童低体重疾病负担分析[J]. 中国儿童保健杂志, 2023, 31(7): 790-793.
[15]	曹亚船, 豆吉娟, 马亚萍, 任金冬, 陈新颜. 肥胖儿童脂质代谢与左心室肥厚及左心室重构的相关性[J]. 中国儿童保健杂志, 2023, 31(7): 809-812.