关键词: 高TSH血症, 转归, 治疗时机

Abstract: Objective To investigate the treatment,outcome and influencing factors of neonatal hyperthyrotropinemia and improve the treatment and follow-up level of hyperthyrotropinemia. Methods Neonates were diagnosed hyperthyrotropinemia in 2012~2014.Some were treated with drug whose concentration of thyrotropin were greater than 15 mU/L.The others were followed up whose concentration of thyrotropin were 6.27～15 mU/L.The follow-up group were splited into two groups with a tangent of 10. Results Two follow-up groups with hyperthyrotropinemia had no significant differences in intelligence,length and natural outcome.The thyroid function of about 80% neonates with hyperthyrotropinemia returned to normal within 6 months. Conclusions 1)84.9% neonates are back to normal on their own whose concentration of thyrotropin are less than 15 mU/L.2)Treatment for neonates should be considered comprehensively whose concentration of thyrotropin are 10~15 mU/L.

Key words: hyperthyrotropinemia, outcome, treatment time