关键词: 25-羟维生素D, 维生素D, 儿童

Abstract: Objective To investigate the nutritional status of vitamin D in children of 0~14 years old for providing reasonable scientific basis of vitamin D supplement for children in Guangzhou. Method ELISA was used to detect serum levels of 25-hydroxy vitamin D[25-(OH)D] in 1 000 children who received physical examination in child health care department of the hospital. Results A total of 634 children were found with deficiency and insufficiency of 25-(OH)D (63.4%), and 366 children were sufficiency of 25-(OH)D (36.6%).The 25-hydroxy vitamin D levels in aged 0~1 and 1~2 groups were much higher than that in the other groups, and the serum 25-(OH)D level decreased with age in children over 2-years old.Serum 25-(OH)D level had statistically significant difference between boys and girls aged 7~14, but no significant difference in aged 0~7.According to seasons, the order of the serum 25-(OH)D level was summer＞autumn＞spring＞winter.97 Children were deficiency or insufficiency of 25-(OH)D in winter (70.29%), which was much higher than that in other seasons(P＜0.05). Conclusion Vitamin D deficiency or insufficiency of children is common in Guangzhou, especially in winter and older children.

Key words: 25-hydroxy vitamin D, vitamin D, children