关键词: 25-羟维生素D, 钙, 磷, 0～6岁儿童, 电化学发光法

Abstract: Objective To explore the relationship between serum levels of 25-hydroxyvitamin D,calcium,phosphorus of 813 children aged 0~6 years and their age in Zhoushan archipelago area. Methods A total of 813 children aged 0~6 years in 2011 were selected.Their serum levels of 25-hydroxyvitamin D,calcium and phosphorus were detected by electrochemistry method,lon-selective electrode method and phosphomolybdic acid uv spectrophotometry method respectively. Results The difference of serum levels of 25-hydroxyvitamin D between male(87.37±38.42) nmol/L and female(89.00±50.58) nmol/L was not significant (t=-0.518,P＞0.05);The difference of serum levels of calcium between male (2.39±0.12)mmol/L and female (2.37±0.09)mmol/L was significant (t=-2.68,P＜0.01);The difference of serum levels of phosphorus between male (1.74±0.08)mmol/L and female (1.77±0.13) mmol/L was significant (t=-3.97,P＜0.01).Both in male and female,the serum levels of 25-hydroxyvitamin D,calcium and phosphorus decreased with age. Conclusions The serum levels of 25-hydroxyvitamin D,calcium and phosphorus show downward trends with age.Given monitor of vitamin D supplements and calcium,phosphorus are important for children aged 2~6 years.

Key words: 25-hydroxyvitamin D, calcium, phosphorus, children aged 0~6 years, electrochemistry method