关键词: 多肽, 胞内肽, 体液内源性肽, 作用方式

Abstract: Peptide is a specifical bioactive substances between amino acids and proteins,which are divided into endogenous peptides and exogenous peptides.Endogenous peptides gain more and more attentions due to the content enrich and various production ways.Recent study revealed that nocoding genes also could code bioactive peptide,and now to find new potential coding open reading frames from lncRNA,rRNA and microRNA is becoming a hot research area.Endogenous peptides could play in many ways,such as binding to its receptor after secretion or working intracellular.As the more application of peptide in the clinic as drugs,there is no doubt that endogenous peptides will have broad application foreground.Here,we make a brief description on the birth and function of peptide,and focus on its new discovery and research progress to provide reference for endogenous peptides research.

Key words: peptide, intracellular peptide, body fluids endogenous peptides, mode of action