关键词: 孕妇, 新生儿, 脐带血, 维生素D

Abstract: Objective To investigate the correlation between neonatal and maternal vitamin D levels and to explore the influencing factors of neonatal umbilical cord blood levels of vitamin D. Methods From November 2015 to March 2016 winter,umbilical venous blood samples were collected from 112 full-term neonates,and venous blood samples were collected from 40 mothers.ELISA was applied to measure the serum 25(OH)D levels and correlative factor analysis was performed. Results The levels of serum 25(OH)D were (6.75±3.59) ng/ml in 112 neonates,vitamin D deficience state was shown in all the neonates.Neonates with moderate and severe vitamin D deficiency accounted for 85.7%.Maternal 25(OH)D levels were positively correlated with neonatal vitamin D levels (r=0.86,P<0.01).The nationality of pregnant women,calcium supplementation during pregnancy,the number of seafood intake,the degree of education and neonatal vitamin D levels were significantly different (P＜0.05).Pregnant women with different gestational weeks,job categories,outdoor activity time,cramps or not during pregnancy and neonatal birth time,the sex of the fetus,birth Methods have no significant difference with neonatal vitamin D levels (P>0.05). Conclusions Vitamin D deficiency is severe among the neonates born in winter,and the level of vitamin D is significantly correlated with the venous blood of the late pregnant women.Pregnant women should be given adequate vitamin D in the third trimester of pregnancy,especially in winter,in order to increase the level of vitamin D in newborn infants.

Key words: pregnant woman, newborn, cord blood, vitamin D