孤独症与肠道菌群失衡的研究进展

doi:10.11852/zgetbjzz2017-25-03-12

中国儿童保健杂志 ›› 2017, Vol. 25 ›› Issue (3): 255-257.DOI: 10.11852/zgetbjzz2017-25-03-12

孤独症与肠道菌群失衡的研究进展

傅锦坚¹,张玉²,李红辉³

柳州市妇幼保健院 1 检验科;
2 保健部;
3 发育行为儿科,广西柳州 545001

收稿日期:2016-10-08 发布日期:2017-03-15 出版日期:2017-03-15
通讯作者: 李红辉,E-maillzfyebzx@126.com
作者简介:傅锦坚(1981-),女,博士学位,主要研究方向为儿童发育障碍。
基金资助:
国家自然科学基金地区科学基金(81460500);柳州市儿童发育障碍疾病研究重点实验室课题

Important roles for the gut microbiome in autism spectrum disorder

FU Jin-jian¹,ZHANG Yu²,LI Hong-hui³

1 Department of Laboratory,2 Department of Public Health,3 Department of Pediatrics Developmental Behavior,Liuzhou Maternity and Child Health Care Hospital,Liuzhou,Guangxi 545001,China

Received:2016-10-08 Online:2017-03-15 Published:2017-03-15
Contact: LI Hong-hui,E-maillzfyebzx@126.com

摘要/Abstract

摘要： 研究显示孤独症谱系障碍(ASD)患者存在明显的胃肠道症状及肠道菌群改变情况,失调的细菌极有可能是ASD疾病发生发展的潜在生物标记物。对肠道微生物的研究,尤其是共生微生物的研究将有助于了解肠道微生物与ASD疾病发生发展的关系。本文就ASD与肠道微生物的关系做一简要综述,为探讨肠道菌群作为ASD靶向治疗的潜在靶点提供理论依据。

关键词: 孤独症谱系障碍, 肠道菌群, 微生态

Abstract: Studies show that most of patients with autism spectrum disorders (ASD) have significant gastrointestinal (GI) symptoms and gut microbiome disorders.These bacterias may be the potential biomarkers of ASD.Studies of microbiome in ASD suggest that changes in the gut microbiome may be associated with ASD and GI disorders in children with ASD.This article reviews the relationship between intestinal bacteria and ASD,and provide a theoretical basis by discussing gut microbiomes as a potential target for ASD therapy.

Key words: gut microbiome, microecology, autism spectrum disorders

中图分类号:

R179

傅锦坚,张玉,李红辉. 孤独症与肠道菌群失衡的研究进展[J]. 中国儿童保健杂志, 2017, 25(3): 255-257.

FU Jin-jian,ZHANG Yu,LI Hong-hui. Important roles for the gut microbiome in autism spectrum disorder[J]. journal1, 2017, 25(3): 255-257.

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孤独症与肠道菌群失衡的研究进展

Important roles for the gut microbiome in autism spectrum disorder

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