中国儿童保健杂志 ›› 2017, Vol. 25 ›› Issue (10): 1027-1029.DOI: 10.11852/zgetbjzz2017-25-10-14

• 综述与讲座 • 上一篇    下一篇

婴幼儿毛细支气管炎发展为哮喘的免疫机制研究进展

智玉萍1,何学明2,董青3   

  1. 蚌埠医学院附属连云港东方医院 1儿科,2心内科,3新生儿科,江苏 连云港 222042
  • 收稿日期:2016-11-05 发布日期:2017-10-10 出版日期:2017-10-10
  • 通讯作者: 董青,E-mail:dqshmu@sina.com
  • 作者简介:智玉萍(1989-),女,山东人,研究生,硕士学位,主要研究方向为儿内科呼吸系统。
  • 基金资助:
    蚌埠医学院创新课题(Byycx1516)

Advances in the research of the immune mechanism of asthma in infants with bronchiolitis

ZHI Yu-ping1,HE Xue-ming2,DONG Qing3   

  1. 1 Department of Pediatrics;
    2Department of Cardiology;
    3 Department of Newborn,Lianyungang Oriental Hospital Affiliated to Bengbu Medical College,Lianyungang,Jiangsu 222042,China
  • Received:2016-11-05 Online:2017-10-10 Published:2017-10-10
  • Contact: DONG Qing,E-mail:dqshmu@sina.com

摘要: 毛细支气管炎是婴幼儿住院的一个重要原因,属于一种婴幼儿较常见的下呼吸道感染,通常被认为是哮喘的第一次发作,与哮喘有着密切的关系,但其主要机制仍不清楚。近年来婴幼儿毛细支气管炎转变为哮喘的机制有较大进展,主要集中在免疫学领域。本文就近年免疫学方面的进展进行综述,以期为基础研究和临床诊疗提供参考。

关键词: 毛细支气管炎, 哮喘, 免疫, 细胞因子

Abstract: Bronchiolitis,a common lower respiratory tract infection in infants,is a major cause of infant hospitalization.Also,bronchiolitis is often considered the first attack of asthma,and has a close relationship with asthma,but its mechanism is still not clear.In recent years,the change of capillary bronchitis in infants and young children has a great progress,mainly in the field of immunology.This article reviews the progress of imm-unology in recent years,in order to provide reference for basic research and clinical diagnosis and treatment.

Key words: bronchiolitis, asthma, immune, cell factor

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