关键词: 极低出生体重儿, 医院感染, 危险因素, 营养素

Abstract: Objective To explore the risk factors and serum nutrient status of very low birth weight infant (VLBWI) with nosocomial infection.Methods Fifty VLBWI with nosocomial infection,from January 2013 to December 2016 in neonatology department of Lianshui County People's Hospital,were enrolled.The levels of serum vitamin A,25-hydroxyvitamin D,calcium,iron,magnesium and zinc were detected.And the related factors such as history,symptoms,signs and laboratory tests were summarized and analyzed.During the same period,50 cases without nosocomial infection were randomly selected as the control group.Results The risk factors for nosocomial infection included smaller than the gestational age,invasive assisted ventilation,invasive operation,out of the ward check,and hospitalized days more than a week,The deficiency rates of zinc,vitamin A and 25-hydroxyvitamin D in hospital infection group were 36.0%,42.0% and 34.0% respectively,which were significantly higher than those in control group (16.0%,22.0%,20.0%;P<0.05).There was no significant difference on calcium,iron and magnesium deficiency rates between the two groups (P>0.05).Conclusion Zinc,Vitamin A and Vitamin D deficiency are common in VLBWI with nosocomial infection.Early detection and treatment should be conducted in order to reduce VLBWI mortality.

Key words: very low birth weight infant, nosocomial infection, risk factors, nutrient