关键词: 并发症, 结局, 死亡原因, 早产儿

Abstract: Objective To investigate the complications and consequences of preterm infants in Henan province, so as to provide basis for improving the poor prognosis of preterm infants. Methods A total of 12 406 live premature infants from 53 hospitals in 17 cities of Henan province, born from January 1st, 2019 to December 31st, 2019, were selected into this study, and their complications and consequences were retrospectively collected and analyzed. Results 1) The most common complication was pneumonia(39.3%), followed by respiratory distress syndrome (34.7%), asphyxia (17.0%), patent ductus arteriosus (13.5%), septicemia (5.6%), intraventricular hemorrhage (5.5%), necrotizing enterocolitis (2.2%), bronchial pulmonary dysplasia (1.7%), periventricular leukomalacia (1.6%), retinopathy of prematurity (1.2%).And the incidence of the above complications except pneumothorax of premature infants was statistically significant among different gestational age groups (P＜0.05).The complication incidence of premature infants in different grades of hospitals was statistically significant (P＜0.05) except the incidence of cholestasis, intracranial infections and persistent pulmonary hypertension of the newborn.2) In terms of treatment outcome, the incidence rates of improvement, abandonment, death and transferring to another hospital of premature infants were 93.4%, 2.6%, 0.8% and 3.2%.The treatment consequences except death rate of premature infants differed significantly in different grades of hospitals(P＜0.01).3) Premature infants most (63.2%) died within 1 week of birth, and the main causes included infectious diseases, respiratory distress syndrome, asphyxia, congenital malformations and pulmonary hemorrhage. Conclusions The complications of premature infants mainly include pneumonia, respiratory distress syndrome, asphyxia, patent ductus arteriosus, septicemia and intraventricular hemorrhage.Gestational age is closely related to the complications and consequences of premature infants.Therefore, it is necessary to further improve the treatment network of all grades, to strengthen prenatal screening and perinatal health care, and to prevent and cure complications positively, thereby improving the prognosis of premature infant.

Key words: complications, consequences, cause of death, premature infants