孤独症谱系障碍早期识别与早期诊断的现状与挑战

doi:10.11852/zgetbjzz2023-0013

中国儿童保健杂志 ›› 2023, Vol. 31 ›› Issue (3): 238-240.DOI: 10.11852/zgetbjzz2023-0013

孤独症谱系障碍早期识别与早期诊断的现状与挑战

柯晓燕

南京医科大学附属脑科医院,江苏南京 210029

收稿日期:2023-02-08 修回日期:2023-02-11 发布日期:2023-02-28 出版日期:2023-03-01
作者简介:柯晓燕(1968-),女,江苏人,主任医师/教授,博士学位,主要研究方向为儿童孤独症等神经发育障碍临床与基础研究。

Status and challenges of early recognition and early diagnosis of autism spectrum disorder

KE Xiaoyan

Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210029, China

Received:2023-02-08 Revised:2023-02-11 Online:2023-03-01 Published:2023-02-28

摘要/Abstract

摘要： 孤独症谱系障碍是严重影响儿童发展的神经发育障碍性疾病,早期识别、早期干预是有效的手段已成为目前的临床共识。本文重点就目前国内外关于孤独症谱系障碍早期识别、早期筛查和早期诊断领域的研究进展及临床实践中尚存的问题进行回顾与讨论,以供相关专业人员参考。

关键词: 孤独症谱系障碍, 早期识别, 早期筛查, 早期诊断

Abstract: Autism spectrum disorder(ASD) is a neurodevelopmental disorder that seriously impacts the development of children. It has become a clinical consensus that early identification and early intervention are effective means. For professional reference, this paper mainly reviews and discusses the progress in early detection, early screening and early diagnosis of autism spectrum disorder in the domestic and overseas researches, as well as the problems in clinical practice.

Key words: autism spectrum disorder, early detection, early screening, early diagnosis

中图分类号:

R749.94

柯晓燕. 孤独症谱系障碍早期识别与早期诊断的现状与挑战[J]. 中国儿童保健杂志, 2023, 31(3): 238-240.

KE Xiaoyan. Status and challenges of early recognition and early diagnosis of autism spectrum disorder[J]. Chinese Journal of Child Health Care, 2023, 31(3): 238-240.

参考文献

[1] Zwaigenbaum L, Bauman ML, Stone WL, et al. Early identification of autism spectrum disorder: Recommendations for practice and research[J]. Pediatrics, 2015,136(Suppl 1):10-40.
[2] Piccininni C, Bisnaire L, Penner M. Cost-effectiveness of wait time reduction for intensive behavioral intervention services in Ontario, Canada[J]. JAMA Pediatr, 2017, 171(1):23-30.
[3] 国家卫生健康委办公厅.0～6岁儿童孤独症筛查干预服务规范(试行)[EB/OL]. (2022-08-23)http://www.gov.cn/zhengce/zhengceku/2022-09/23/content_5711379.htm
[4] Hickey E, Sheldrick RC, Kuhn J,et al.A commentary on interpreting the United States preventive services task force autism screening recommendation statement[J]. Autism, 2021, 25(2):588-592.
[5] Maenner MJ, Shaw KA, Bakian AV, et al. Prevalence and characteristics of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2018[J]. MMWR Surveill Summ, 2021,70(11):1-16.
[6] Brown M, Matson J, Tevis C. Methods of screening for core symptoms of autism and pervasive developmental disabilities[M]// Matson JL, Sturmey P. Handbook of Autism and Pervasive Developmental Disorder. Autism and Child Psychopathology Series. Cham: Springer, 2022.
[7] Hirota T, King BH.Autism spectrum disorder: A review[J]. JAMA, 2023, 329(2):157-168.
[8] Chlebowski C, Robins DL, Barton ML, et al. Large-scale use of the modified checklist for autism in low-risk toddlers[J]. Pediatrics, 2013, 131(4):e1121-e1127.
[9] Kim SH, Joseph RM, Frazier JA, et al. Predictive validity of the Modified Checklist for Autism in Toddlers (M-CHAT) born very preterm[J]. J Pediatr, 2016, 178:101-107.
[10] 美国0-3团队. DC:0-5婴幼儿与儿童早期心理及发育障碍诊断分类[M].柯晓燕,译.南京:江苏凤凰科学技术出版社,2021.
[11] Dawson G, Rieder AD, Johnson MH. Prediction of autism in infants: Progress and challenges[J/OL].Lancet Neurol, 2022.doi:10.1016/S1474-4422(22)00407-0.
[12] Shen L, Liu X, Zhang H, et al. Biomarkers in autism spectrum disorders: Current progress[J].Clin Chim Acta, 2020, 502:41-54.

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孤独症谱系障碍早期识别与早期诊断的现状与挑战

Status and challenges of early recognition and early diagnosis of autism spectrum disorder

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