journal1 ›› 2015, Vol. 23 ›› Issue (8): 859-861.DOI: 10.11852/zgetbjzz2015-23-08-24

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Investigation of perinatal birth defects from 2001 to 2013 in Pingyin,Shandong province.

XU Xin1,LI Shi-xue1,ZHAO Si-qi1,YU Zhi-xia2.   

  1. (1 School of Public Health,Shandong University,Jinan,Shandong 250012,China;2 Maternal and Child Health Care Hospital of Pingyin,Jinan,Shandong 250400,China)
    Corresponding author:LI Shi-xue,E-mail:shixueli@sdu.edu.cn
  • Received:2015-03-10 Online:2015-08-10 Published:2015-08-10
  • Contact: LI Shi-xue,E-mail:shixueli@sdu.edu.cn

山东省平阴县2001-2013年围产儿出生缺陷调查分析

徐昕1,李士雪1,赵思琪1,喻支霞2   

  1. 1 山东大学公共卫生学院,山东 济南 250012;
    2 济南市平阴县妇幼保健站,山东 济南 250400
  • 通讯作者: 李士雪,E-mail:shixueli@sdu.edu.cn
  • 作者简介:徐昕(1989-),女,山东人,硕士研究生在读,主要研究方向为社会医学。

Abstract: Objective To analyze the data of birth defects from 2001 to 2013 in Pingyin,and to provide a basis for making effective interventions to reduce birth defect ratio. Methods The datas of perinatal in Pingyin nearly 14 years were investigated and collected,the birth ratio,categories and relevant factors were analyzed in descriptive statistical methods. Results The perinatal birth defects ratio was 10.8‰,the prenatal diagnosis ratio was 20.7%.The top five birth defects categories were hydrocephalus,hypospadias,deformity of external ears,cleft lip and palate,kidney malformation.The male birth defect ratio was higher than that of female,the multiple births was higher than single birth,the maternal age <20 and >35 were higher than other age groups (P all<0.05),there was no significant difference between urban and rural areas. Conclusions The birth defects is related to gender,maternal age as well as the embryo number.The birth defects ratio in Pingyin is lower than the average of China.The prenatal diagnosis rate should be raised for reducing the birth defects.There is great potential for the development of prenatal diagnosis technologies.

Key words: perinatal, birth defects, analyze

摘要: 目的 分析平阴县2001-2013年出生缺陷发生情况,为制定降低出生缺陷发生的干预措施提供依据。方法 调查收集平阴县近14年来围产儿出生缺陷资料,运用描述性统计分析方法分析出生缺陷发生率、缺陷种类及相关因素。结果 平阴县出生缺陷平均发生率为10.8‰,产前诊断率为20.7%。出生缺陷病种占前五位的是脑积水、尿道下裂、副耳、唇裂合并腭裂、肾脏畸形。男性出生缺陷发生率高于女性;产妇年龄>35岁的出生缺陷发生率高于其他年龄组;双(多)胎妊娠出生缺陷发生率高于单胎妊娠(P<0.05);农村和城镇的地区差异无统计学意义。结论 出生缺陷发生率与围产儿性别、产妇年龄、孕母怀孕胎数具有相关性,与城乡地区分布不具有相关性。平阴县出生缺陷发生率低于全国平均水平,但产前确诊率有待进一步提高,运用多种方法的产前诊断技术仍有很大的发展空间。

关键词: :围产儿, 出生缺陷, 分析
中图分类号:R174 文献标识码:A 文章编号:1008-6579(2015)08-0859-03 doi:10.11852/zgetbjzz2015-23-08-24

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