Abstract: Objective To understand the infantile nocturnal sleep-wake pattern developmental trajectory with Actiwatch,and to be benefit to the clinical assessment of infantile sleep. Methods Longitudinal study was conducted between October,2009 and October 2011 in Maternal and Child Health Care Hospital of Haidian district.Actiwatch was used to track the sleep-wake pattern development trajectory of health infants in the first year of life in the home setting.Participating infant were followed up at monthly from the 1~6 months after birth,and then at 9 months and 12 months of age respectively.Meanwhile,infantile sleep was observed continuously for about 60 hours at each visit.Data of 32 infants were collected with Actigraphy. Results With infants' age increasing,the nocturnal sleep duration(366.07~497.04 min)and the longest continuous interval (213.21~381.10 min)increased.Compared with the first month,the nocturnal sleep duration at 5 months increased 102.57 minutes,the longest continuous sleeping interval at 6 months increased 99.39 minutes,these differences were statistically significant (t=4.12,5.45,P＜0.05).The latency of infants' nighttime sleeponset (56.85~15.13 min)and the number of nighttime awakening(2.83~1.60 times) decreased with age.Compared with the first month,the latency of infants' nighttime sleep onset at 4 months decreased 29.65 minutes,the numbers of nighttime awakening at 5 months decreased 0.36 times,these difference were statistically significant (t=9.47,3.51,P＜0.05).There were no significant differences between adjacent ages and sex. Conclusions During the first 4~6 months after birth,infantile sleep-wake pattern undergo obvious change.The capability of sleep-onset and uninterrupted sleep improve with age.

Key words: sleep, longitudinal study, infants

摘要： 目的 应用Actiwatch评估婴儿出生后第一年夜晚睡眠-觉醒模式发展变化轨迹,为评估指导婴儿早期睡眠提供参考依据。方法 调查2009年10月-2011年10月期间,在北京市海淀区妇幼保健院分娩的32例婴儿在家庭自然环境状态下前瞻性追踪婴儿0~12个月的夜晚睡眠-觉醒模式的发展轨迹,监测年龄点包括出生后1~6、9、12月龄各1次,共8次。观察时间为每次60 h。通过Actiwatch腕表式活动记录仪采集各监测年龄点的睡眠-觉醒信息。结果 随着年龄的增长,婴儿夜晚总睡眠时间(366.07~497.04 min)和最长连续睡眠时间(213.21~381.10 min)逐渐延长,婴儿夜晚总睡眠时间5月龄与出生后1月龄相比增加了102.57 min、最长连续睡眠6月龄与1月龄相比增加了99.39 min,差异均有统计学意义(t=4.12、5.45,P均＜0.05)。婴儿的入睡潜伏期(56.85~15.13 min)和夜晚觉醒次数(2.83~1.60次)随月龄增长呈下降趋势,婴儿入睡潜伏期4月龄相比1月龄降低了29.65 min、夜晚觉醒次数5月龄相比1月龄减少了0.36次,差异均有统计学意义(t=9.47、3.51,P均＜0.05);相邻年龄点比较及不同性别比较差异均无统计学意义。结论 海淀区海淀街道婴儿夜晚睡眠-觉醒模式在生后4~6个月内变化发展最为迅速,随年龄增长婴儿夜晚入睡能力和连续睡眠能力增强。

关键词: 睡眠, 纵向研究, 婴儿