Abstract: Objective To analyze the epidemiological characteristics of Hand-foot-mouth disease (HFMD) in Wanzhou district of Chongqing,and provide the scientific evidence for prevention and control of HFMD. Method The data with descriptive epidemiology method were analyzed. Results Totally 11 304 HFMD case were reported in Wanzhou district from 2009 to 2015,including 77 severe cases and 12 death cases.Most of these cases were scattered-living children (63.35%) and childcare children (32.27%),aged from 0 to 5 years old (93.57%).The epidemic curve showed as double-peak curve,One was from May to July,and the other one was from November to December.All of the 430 HFMD laboratory-confirmed cases,EV71 virus accounted for 45.58%,CoxA16 accounted for 28.37%,other enterovirus accounted for 26.05%. Conclusions Wanzhou district has the high morbidity level from 2009 to 2015,the main pathogens are other enterovirus and EV71.In order to restrain the HFMD outbreak and epidemic,the comprehensive prevention and control measures in key areas and populations are necessary in the high-incidence season.

Key words: hand-foot-mouth disease, epidemiology, etiology

摘要： 目的 通过分析2009-2015年万州区手足口病的流行特征,为制定有效防控措施提供科学依据。方法 运用描述性流行病学方法对资料进行分析。结果 万州区2009-2015年累计报告手足口病11 304例,其中重症77例,死亡12例。发病年龄主要为5岁以下儿童,占发病数的93.57%,散居儿童和幼托儿童分别占发病总数的63.35%和32.27%。于5-7月和10-12月出现两个发病高峰。430例实验室诊断病例中,肠道病毒EV71阳性196例(占45.58%),Cox A16阳性122例占(28.37%),其它肠道病毒阳性112例(占26.05%)。结论 2009-2015年万州区手足口病高发,病原体以EV71为主,需在5-7月和11-12月对重点地区和人群采取综合防控措施,以降低手足口病的暴发和流行。

关键词: 手足口病, 流行病学, 病原学