journal1 ›› 2019, Vol. 27 ›› Issue (8): 857-860.DOI: 10.11852/zgetbjzz2018-1467

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Factors in determining the initial colonization of intestinal microbiota in infants

NIE Yao1, WANG Zhao-xia2   

  1. 1 Department of Pediatric Gastroenterology,the First Bethune Hospital of Jilin University,Changchun, Jilin 130021,China;
    2 Shenzhen Children′s Hospital,Shenzhen,Guangdong 518038,China
  • Received:2018-10-16 Online:2019-08-10 Published:2019-08-10
  • Contact: WANG Zhao-xia,


聂瑶1, 王朝霞2   

  1. 1 吉林大学白求恩第一医院小儿消化内科,吉林 长春 130021;
    2 深圳市儿童医院,广东,深圳 518038
  • 通讯作者: 王朝霞,
  • 作者简介:聂瑶(1993-),女,湖北人,硕士在读,主要研究方向小儿消化系统疾病的诊治。

Abstract: Normal microbiota of the intestinal tract plays an important role in human health and disease. The alterations in microbial population and profile caused by certain factors may disturb normal physiological functions of human. In this review,the effects of factors on intestinal microbiota were extensively discussed,including gestational age,delivery route,feeding mode,growth environment,antibiotic use,bacterial interference,and application of probiotics.

Key words: normal intestinal microbiota, initial colonization, infants

摘要: 肠道菌群与宿主的健康和疾病有极为密切的关系,多种因素可干扰肠道菌群的构成进而影响宿主的正常生理功能。本文将探讨胎龄、分娩方式、喂养方式、生长环境、抗生素应用、细菌间相互作用和微生态制剂的使用等诸多因素对婴幼儿肠道菌群初始定植的影响。

关键词: 肠道正常菌群, 初始定植, 婴幼儿

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