journal1 ›› 2020, Vol. 28 ›› Issue (10): 1110-1113.DOI: 10.11852/zgetbjzz2020-0293

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Influencing factors of gut microbiota of infants and its function in intestinal immunity

SUN Yan-ting, LIANG Hong-tao, WANG Chen, YAO Yi-bo, LU Jin-gen   

  1. Department of Anal and Intestinal Diseases,Longhua Hospital,ShanghaiUniversity of Traditional Chinese Medicine,Shanghai 200032,China
  • Received:2020-02-29 Revised:2020-04-07 Online:2020-10-10 Published:2020-10-10
  • Contact: LIANG Hong-tao,E-mail:hongtao.liang@shutcm.edu.cn

婴幼儿肠道菌群的影响因素及其在肠道免疫中的作用

孙琰婷, 梁宏涛, 王琛, 姚一博, 陆金根   

  1. 上海中医药大学附属龙华医院肛肠科,上海 200032
  • 通讯作者: 梁宏涛,E-mail:hongtao.liang@shutcm.edu.cn
  • 作者简介:孙琰婷(1995-),女,硕士研究生在读,主要从事中西医结合肛肠疾病临床研究工作。
  • 基金资助:
    国家自然科学基金(81603624);上海市进一步加快中医药事业发展三年行动计划(ZY(2018-2020)-CCCX-1007);上海中医药大学优秀本科生跟踪本硕博一体化培养计划(沛然计划)(教学420);全国中医学术流派传承工作室第二轮建设项目(国中医药人教函[2019]62号)

Abstract: Gut microbiota will experience a series of evolutions to form the final microbial homeostasis once it adapts to colonize in the intestinal tract.This review focuses on the gut microbiota in infants altered by factors in many aspects,for example,the stage of parturition,feeding patterns,dietary structure,living environment,diseases and drug use.In addition,the important role of gut microbiota in the formation of intestinal immunity is discussed.

Key words: infants, gut microbiota, influencing factors, immunoregulation

摘要: 婴幼儿肠道菌群自定植起,随着年龄增长,需历经多次改变才能最终形成微生物稳态。本文主要介绍婴幼儿肠道菌群受分娩阶段、喂养方法、饮食结构、生活环境、疾病因素、药物使用后发生的改变,及其在肠道免疫功能形成中发挥的重要作用。

关键词: 婴幼儿, 肠道菌群, 影响因素, 免疫调节

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