Chinese Journal of Child Health Care ›› 2022, Vol. 30 ›› Issue (8): 874-878.DOI: 10.11852/zgetbjzz2021-0395

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Research progress on the effect of drug therapy on the physical growth of children and adolescents with attention-deficit/hyperactivity disorder

DENG Lan-liu, CHEN Li   

  1. Growth, Development and Mental Health Center for Children and Adolescents, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders;Ministry of Education Key Laboratory of Child Development and Disorders; China International Science and Technology Cooperation Base of Child Development and Critical Disorders; Chongqing Key Laboratory of Translational; Chongqing Key Laboratory of Child Nutrition and Health, Chongqing 400014, China
  • Received:2021-03-22 Revised:2021-05-13 Online:2022-08-10 Published:2022-08-17
  • Contact: CHEN Li,E-mail: chenli@cqmu.edu.cn

药物治疗对注意缺陷多动障碍患儿体格生长影响的研究进展

邓岚柳, 陈立   

  1. 重庆医科大学附属儿童医院儿童青少年生长发育与心理健康中心/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室/儿童发育重大疾病国家国际科技合作基地/认知发育与学习记忆障碍转化医学重庆市重点实验室/儿童营养与健康重庆市重点实验室,重庆 400014
  • 通讯作者: 陈立,E-mail: chenli@cqmu.edu.cn
  • 作者简介:邓岚柳(1995- ),女,四川人,住院医师,在读硕士研究生,主要研究方向为儿童发育障碍性疾病。
  • 基金资助:
    重庆市科卫联合医学科研项目重点项目(2018ZDXM012)。

Abstract: Attention-deficit/hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder in childhood, which has a significant impact on children's academic performance, interpersonal communication, social functioning, as well as the whole family and society.The incidence of ADHD has been on the rise over the past few decades.Stimulants such as methylphenidate (MPH) and selective norepinephrine reuptake inhibitors such as atomoxetine (ATX), are both commonly used drugs in ADHD treatment.Parents are concerned about the possible negative effects of medication on the physical growth of ADHD children.This article reviews the effects, mechanisms and management of drug therapy on the physical growth of ADHD children, in order to improve the compliance of clinical drug therapy.

Key words: attention-deficit/hyperactivity disorder, drug therapy, physical growth, management

摘要: 注意缺陷多动障碍(ADHD)是儿童时期最常见的神经发育障碍性疾病,对儿童的学业水平、人际交往、社会功能以及整个家庭、社会都有不可忽视的影响。ADHD的发病率在过去几十年里一直呈上升趋势。兴奋剂哌甲酯(MPH)与选择性去甲肾上腺素再摄取抑制剂托莫西汀(ATX)均为治疗ADHD公认的一线药物。药物对ADHD儿童体格生长可能带来的消极影响令家长担忧。本文就药物治疗对ADHD患儿体格生长的影响、相关机制及管理进行综述,以期提高患儿临床药物治疗的依从性。

关键词: 注意缺陷多动障碍, 药物治疗, 体格生长, 管理

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