journal1 ›› 2017, Vol. 25 ›› Issue (4): 369-371.DOI: 10.11852/zgetbjzz2017-25-04-13

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Effect of maternal nutrition on asthma,wheeze,and hereditary allergic diseases outcome in offspring during childhood

YAN Si-you,XU Rong-xian   

  1. Department of Nutrition and Food Hygiene,School of Public Health,Fujian Medical University,Fuzhou,Fujian 350122,China
  • Received:2016-05-23 Online:2017-04-10 Published:2017-04-10

孕期营养对儿童期哮喘及遗传性过敏性体质发生的影响

严思悠,许榕仙   

  1. 福建医科大学公共卫生学院营养与食品卫生学系,福建 福州 350122
  • 通讯作者: 许榕仙,E-mail625680591@qq.com
  • 作者简介:严思悠(1993-),女,研究生在读,主要研究方向为肿瘤流行病学。
  • 基金资助:
    福建省自然科学基金(2012J01359)

Abstract: More and more epidemiological investigation and animal experiment indicated that the maternal nutrition has associated with the risk of developing adult offspring's non-infectious diseases in later life.These findings showed that the unbalanced maternal nutrition not only arouses their adult offspring non-infectious diseases,but also influences the risk of developing their offspring's asthma,gasp,and hereditary allergic constitution in childhood.These diseases will bring about psychological burden to the children,and seriously influence their growth,development and living quality,accompanied with life danger.However,many researches indicated that the rational nutrition and scientific diet during the pregnancy can reduce the morbidity risk of these diseases of the offspring.This paper makes simple summary for the effects of maternal nutrition on asthma,wheeze,and hereditary allergic diseases outcome in offspring during childhood.

Key words: childhood, asthma, wheeze, allergic, maternal, nutrition

摘要: 20世纪90年代 Barker DJ提出健康与疾病发育起源的学说,越来越多的流行病学调查及动物实验提示母亲孕期营养对其子代成年以后非感染性疾病(代谢性综合征及心肺疾病等)的发生有着重要的联系。而也有一些调查研究发现母亲孕期营养可能引起子代成年时期非感染性疾病,还可能影响子代儿童时期非感染性疾病的发生,如儿童哮喘,喘息,遗传性过敏体质等。这些疾病带给患儿心理负担,严重影响患儿生长发育、生活质量并伴有生命危险。然而大量的研究提示孕期合理营养,科学膳食可以降低子代这些疾病的发病风险。我国目前生活质量提高,现如今多数孕妇营养摄入不平衡,或处饱和甚至过剩状态,而儿童过敏性疾病的发生逐年增加。本文就孕期营养对子代儿童期哮喘,喘息及遗传性过敏性体质发生的影响做一简要的综述。

关键词: 儿童期, 哮喘, 喘息, 遗传性过敏体质, 孕期, 营养

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