Abstract: Objective To investigate the screening and follow-up stituation of retinopathy of prematurity (ROP) in maternal and child health care hospital, so as to provide suggestions for improving the quality of screening and follow-up. Method Screening, follow-up and intervention data of 3 579 premature infants, who were screened for ROP and met the screening criteria in triple A maternal and child health hospitals from January 1st to December 31st in 2019, were retrospectively investigated by referring to inpatient medical records, outpatient registration and ROP management files. Result The detection rate of ROP was 11.2%(400/3 579), 3.4% in stage 1, 6.2% in stage 2, and 1.6% in stage 3 and above. With the decrease of gestational age and birth weight, the detection rates of ROP and severe ROP increased. The detection rate of ROP in infants at corrected gestational age (week)of 31 ~ and 32 ~ group was higher in the first screening. The intervention rates of infants with ROP stage 1 and stage 2 were 1.6% and 1.7%, respectively, lower than 30.9% for ROP stage 3. The main intervention method was vitreous injection of drugs (91.3%). The settlement rate of all positive cases was 41.2%. The case settlement rate of infants with ROP stage 1 and stage 2 was 51.7% and 40.8%, respectively, higher than 21.8% for stage 3. Conclusion Maternal and child health care hospitals should improve the service capacity of eye care, strengthen ROP screening, improve the project management, regular follow-up, intervention of children with ROP and referral of positive cases to reduce the occurrence of adverse outcomes.

Key words: retinopathy of prematurity, screening, follow-up

摘要： 目的 调查妇幼保健院早产儿视网膜病变(ROP)的筛查及随访情况,为提高筛查和随访质量提供建议。方法 通过查阅住院病案、门诊登记及ROP管理档案,回顾性调查2019年1月1日—12月31日在某3个三级甲等妇幼保健院进行ROP筛查且符合筛查标准的3 579例早产儿的筛查、随访和干预情况。结果 ROP检出率为11.2%(400/3 579),1期为3.4%,2期为6.2%,3期及以上为1.6%。随着孕周、出生体重的降低,ROP检出率、重症ROP检出率升高。首次筛查矫正胎龄(周)为31~、32~组ROP检出率较高。ROP 1期、2期患儿干预率分别为1.6%、1.7%,低于3期的30.9%。干预方式主要采用玻璃体腔注射药物治疗(占91.3%)。全部阳性病例随访患儿的结案率为41.2%。1期、2期患儿结案率分别为51.7%、40.8%,高于3期的21.8%。结论 妇幼保健院应提升眼保健专科服务能力,加强ROP筛查,完善ROP患儿专案管理,做好筛查阳性病例的定期随访、干预、转诊工作,减少不良结局的发生。

关键词: 早产儿视网膜病变, 筛查, 随访