%0 Journal Article %A CHEN Ling %A CHEN Ying-rui %A LI Hong-hui %A LIU Ping %A LUO Li %A WEI Wen-xi %A ZENG Ting %A ZHANG Yu %A QUAN Yan %T Functional near-infrared spectroscopy study in children with developmental delay %D 2021 %R 10.11852/zgetbjzz2021-0208 %J Chinese Journal of Child Health Care %P 772-774 %V 29 %N 7 %X Objective To study the characteristics of children with developmental delay (DD) by using functional near infrared spectroscopy (fNIRS), so as to provide reference for the individual diagnosis and treatment of DD. Methods A total of 13 children with DD(DD group) and 19 normal children (NC group) were selected in this study, whose brain function was tested by 8-channel fNIRS. Multiscale entropy (MSE) of each channel and the mean MSE of the frontal region between DD group and NC group were compared by t test. Results The mean MSE of DD group (1.570±0.491) was significantly lower than that of NC group (2.075±0.791) (t=2.228, P=0.034). The MSE values in channel 3 and 8 were significantly different between DD group and NC group(t=2.513, 2.868, P<0.01). Conclusions Compared with the normal control group, the complexity of frontal lobe spontaneous brain signals in children with DD is significantly lower, indicating that children with DD have bilateral prefrontal brain function impairment. %U https://manu41.magtech.com.cn/Jwk_zgetbjzz/EN/10.11852/zgetbjzz2021-0208