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Table of Content

    06 August 2011, Volume 19 Issue 8
    Effect of maternal and child health care program for urban migrant population on the state of health care service of migrant children in Beijing
    YAN Shu-juan, CHEN Xin-xin
    2011, 19(8):  689-691. 
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    【Objective】 To analyze the effect of maternal and child health care(MCH) program for urban migrant population on the state of health care service of migrant children in Beijing. 【Methods】 Eleven communities were chosen in Chaoyang and Daxing district by stratified cluster sampling to implement a five-year MCH program for urban migrant population. At the end of the program, caretakers of migrant children were randomly chosen in the communities to answer a questionnaire. Data were compared with the baseline. 【Results】 There were 1 005 migrant children involved in the terminal survey. The results showed that: 1)The awareness rate of child health service and knowledge of child health increased significantly among the caretakers of migrant children. 2)The utilization of health care service for migrant children improved significantly. The rates of having child health care record, health care coverage and system management significantly improved than the baseline. The increased rate was 71.7%, 76.2% and 87.5% respectively. 3)The health states of migrant children were significantly improved than the baseline. The prevalence of diarrhea within 2 weeks of migrant children was lower than the baseline, and so was the prevalence of cough within 2 weeks. 【Conclusion】 The implement of the MCH program for migrant population have significant roles in improving the health knowledge of the caregivers, and in improving the health services and health state of migrant children.
    Use of supplemental vitamin D in fully breasted infants in Shandong province
    BI Xiao-na, YI Ming-ji, RAN Ni
    2011, 19(8):  692-694. 
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    【Objective】 To investigate the rate of vitamin D supplementation and related factors in fully breasted children in Shandong province. 【Methods】 A total of 903 children who came to vaccination clinics for planned immunity and health care were selected from November 2010 to January 2011. 612 fully breasted subjects as responders. Their use of vitamin D supplementation and related factors were investigated with self-made questionnaire. 【Results】 The rate of vitamin D supplements use in fully breasted children was 76.6%. The infant intake of 166.0 to 700.0 U/day of vitamin D supplementation began at 30.0(30.0) days after birth and disused at 9.0(7.0) months. The vitamin D supplements adding rate of children who born after one week, 1 to 2 weeks, 2 to 4 weeks and more than 4 weeks was 1.7%, 3.4%, 9.3%and 85.5% respectively. The prevalence of vitamin D supplement disuse was 78.4% in infants within 1 year old , 16.6% during 1 to 2 years old and 5.1% during 2 to 3 years old. The multi-factors Logistic regression analyses suggested that use of vitamin D supplements was significantly associated with ages, family income level, maternal level of education and nutrient intake during pregnancy(OR=0.673,0.706,1.651,1.646). 【Conclusions】 The vitamin D supplements use in fully breasted children is widespread, but its application is not standard according to the requirements of domestic and international vitamin D supplements application guidelines. Age, income level and other factors affect vitamin D supplements use.
    Longitudinal study of growth and development and physical deviation tendency about schoolchildren in Changsha city
    KANG Ru-tong, ZHONG Yan, JIANG Yao-hui
    2011, 19(8):  695-697. 
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    【Objective】 To study the longitudinal growth law and physical deviation tendency about schoolchildren in Changsha city and to provide longitudinal fundamental data for children's growth and development research. 【Methods】 889 schoolchildren were followed longitudinally from grade 1 to grade 6. Anthropometric measurements of height, weight were obtained for each child once one year. Their nutritional status and height grade were evaluated by 2005 children children and adolescents growth standard.The physical growth velocities and change of physical deviation ratio were calculated .At the same time, the physical growth level was comparison with China national standard. 【Results】 1)The height average velocities were 5.3~6.2 cm/year in boys and 5.5~7.0 cm/year in girls and the accelerated growth were seen at 11 years in boys and 9 years in girls. The weight velocities were more as the age rised and obviously more after 10 years for boys and girls. 2)For boys and girls, the average height in the different age groups were lower than China national standard and the gap gradually reduced as the age rised. The average weight of boys and girls under 8 years were also lower than China national standard, but catch up and more than China national standard after 8 years. 3)As the age rised, their rates of short stature and wasting decreased, in contrast, their rates of obesty and over-weight increased, There were significant difference among age groups. 【Conclusions】 The physical growth is followed basic law for schoolchildren in Changsha city, but weight velocities are more than height velocities. The average height in the different age schoolchildren in Changsha city are slower than China national standard.It should be pay attention to rapid increase of obesity and over-weight children.
    Analysis of the intellectual characteristics and affecting factors in patients with congenital hypothyroidism
    YANG Hai-he, ZHANG Yu-min, QIU Lei, KONG Yuan-yuan, ZHAO Juan
    2011, 19(8):  698-700. 
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    【Objective】 Through exploring the intellectual characteristics of patients with congenital hypothyroidism(CH) diagnosed by neonatal screening program and analyzing the relations between intelligence and the disease itself or therapy factors, and to provide a basis for more exactly evaluating the outcomes and exploring more perfect therapeutic schedule. 【Methods】 The subjects were the CH patients aged from 7 to 18 years old. Intelligence tests were completed in all patients using China Wechsler intelligence scale for children(C-WISC). The patients' intelligence quotients were compared with those of normal population. Statistic analyzing was conducted using the SPSS 13.0 statistic software for Windows. 【Results】 The difference between intelligence quotients(IQ) of CH patients and standard value of normal population(100±15) was not significant(P>0.05). The IQ of CH patients had significant or very significant positive correlation with T4 concentrations at the time of CH were diagnosed, the severity of thyroid gland hypoplasia, level of restoring thyroid function at the beginning of therapy(r=0.336~0.660, P=0.024~0.000) and a negative correlation with the age of initial treatment(r=0.295,P=0.049). 【Conclusions】 The intelligence distribution characteristic of CH patients is consistent with the normal population. The important factors affecting the intellectual development in CH patients were severity of CH and level of restoring thyroid function at the beginning of therapy.
    Mutation study of fragile X mental retardation 1 in Chinese Han autism spectrum disorder children
    LIU Xian, CHEN Yan-ping, ZHOU Xue, WANG Xue-lai , SUN Meng, LIANG Shuang, WU Li-jie
    2011, 19(8):  701-703. 
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    【Objective】 To analyze the mutation condition of fragile X mental retardation 1(FMR-1) in Chinese Han autism spectrum disorder(ASD) children using optimized PCR system and STR fluorescence technology. 【Methods】 From January 2007 to October 2010, 466 Chinese Han ASD children were recruited for this study by the Children Development Behavior Research Center of Harbin Medical University. Among 466 Chinese Han ASD children, 433 children were diagnosed as typical autism; 33 children were diagnosed as pervasive developmental disorder-not otherwise specified(PDD-NOS). Total genomic DNA was extracted from peripheral blood leukocytes(3 to 5mL whole blood), and PCR amplifications were performed in a total volume of 25 μL containing 50 ng of genomic DNA. The expanded range of allele sizes were detected by gel visualization and STR fluorescence technology. 【Results】 464(99.57%)PCR products of ASD children were amplified successfully. Those PCR implications which fragment size was less than 500 bp, were further verified by STR fluorescence technologies. At the same time, the DNA samples of two autism patients(0.43%) were not amplified successfully by PCR, excluding the possibility of DNA quality and operational problems, and deduced them as abnormal mutation of fragile X mental retardation 1(FMR-1). 【Conclusions】 Using optimized PCR system and STR fluorescence technology can significantly provide the CGG repeat numbers of alleles. The incidence of the mutation of FMR-1 gene in the Chinese Han ASD children is 0.43%.
    Epidemiological study on unintentional injuries among migrant children under six years old in four communities in Beijing
    XU Tao, ZHANG Rui, LIANG Yi, GONG Li-min, WANG Hui-shan
    2011, 19(8):  704-706. 
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    【Objective】 To understand the situation of unintentional injuries among migrant children under six years old in Beijing and provide basis for future intervention. 【Methods】 Four migrant communities in Beijing were randomly selected to participate in the study. Questionnaire survey was conducted among parents of migrant children under six years old. Parents of resident children were also interviewed as the control group. The contents of the questionnaire survey included unintentional injuries related knowledge and behavior, occurrence of unintentional injuries in the previous year. 【Results】 The general incidences of unintentional injuries among migrant and resident children were 11.9% and 12.9% respectively. There was no statistically significant difference between the two groups(χ2=0.119,P=0.730). The incidences of road traffic injuries, sharp instrument injuries, burns and bites were higher among migrant children than resident children. 40.5% of injuries among migrant children happened at home, 26.2% at outside activity spots, 33.3% at road sides or other outside places. 92.3% of injuries among resident children happened at home. The average time of hospital admission, rest time and medical cost due to injuries among migrant children were significant higher than those of the resident children. 【Conclusions】 There are specific epidemiological characters on unintentional injuries among migrant children under six years old in Beijing. The disease burden of unintentional injuries among migrant children is higher than resident children. Intervention methods should be taken to decrease the incidence and burden of unintentional injuries among migrant children.
    Canonical correlation analysis on body shape and quality indicators of preschool children in Beijing
    LI Yi-chen, PAN Ying
    2011, 19(8):  707-709. 
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    【Objective】 To study the relationship between body shape and physical quality indicators of preschool children. 【Methods】 6 405 preschool children were tested on body shape including height, sit high, weight, chest circumference, skinfold thickness, and physical quality indicators which include standing long jump, throw for distance, seat proneness, the time of shuttle run, walk balance beam and feet consecutive jump. Data were analyzed by canonical correlation analysis. 【Results】 First pair canonical variables was selected by canonical correlation analysis and its coefficient was 0.760. The canonical variables representing the body shape indicators were height, chest circumference, abdominal skinfold thickness and weight. Among these indicators, height played the most important role. The canonical variables representing the physical quality indicators were standing long jump, throw for distance and the time of shuttle run, standing long jump played the most important role. Height and chest circumference were positive to physical quality, while abdominal skinfold thickness and weight were negative to physical quality. 【Conclusions】 Correlationship is found between the body shape and the physical quality in preschool children. Height and standing long jump play the most important roles.
    Investigation of disease spectrum of children psychological outpatient in general hospital during 2001-2010
    XIAO Li-jun, LUO Li, ZHANG Qian, AN Yu-lin, FENG Zhi-chun
    2011, 19(8):  710-712. 
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    【Objective】 To investigate the features of disease spectrum of children and juvenile psychological outpatient in general hospital, and to supply important theory basis of mental health work. 【Methods】 General information of 1 666 first-visit case files in Bayi Children's Hospital during 2001-2010 were statistically analyzed in terms of annual distribution tendency of case number, patients' age and sex. Disease-type was classified according to The International Statistical Classification of Diseases and Related Health Problems 10th Revision(ICD-10) based on the first diagnose, and the top 5 mono disease and proportions were screen out from two categories. 【Results】 170 cases(17.7% of the classificatory cases, 10.2% of total cases, the same below)of F32(depressive episode), 123 cases(12.8%,7.4%)of F98(behavioral and emotional disorders with onset usually occurring in childhood and adolescence), 116 cases(10.8%,7.0%)of F31(bipolar disorder), 104 cases(10.8%,6.2%)of F41(other anxiety disorders)and 100 cases(10.4%,6.0%)of F20(Schizophrenia)occupied the first 5 positions of mental and behavioral disorders; 133 cases(18.9%,8.0%)of depression, 112 cases(15.9%,6.7%)of anxiety, 87 cases(12.4%,5.2%)of problems of family, 81 cases(11.5%,4.9%)of study-weariness and 75 cases(10.7%,4.5%). Internet addiction occupied the first 5 positions of psychological problems. 【Conclusions】 The data of psychological outpatient increased significantly, 16~18 is high-risk population. Anxiety and Depression disorders are still most important work. Problem solving of interpersonal relationship and family is an effective way to reduce the incidence of psychological problems.
    Study on correlation between the child's bone mineral density with seasons and ages
    LIU Li,ZHENG Zheng
    2011, 19(8):  713-715. 
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    【Objective】 To investigate the present situation of child's bone mineral density(BMD) in north china, and the relationship between child's BMD with ages, gender and seasons. 【Methods】 Analyzed the BMD and whose relationship with ages, gender and seasons of 5 971 normal children who came to our health center for body check in 2008-2009. 【Results】 The distribution of child's BMD normal and increased with the actual month. The relationship was linear and the difference was significant(P <0.001). BMD in different ages had significant difference. The relationship between BMD and gender was not significant before puberty(P>0.05). Only in adolescent ages BMD of girls was higher than boys and the difference was high significant(P<0.000 1). Child's BMD's Z-score had not significant difference in different seasons except of school age children.BMD's Z-score of infancy was lower in autumn than winter, and the difference was significant(P<0.05). Child's BMD's Z-score of school ages was lower in summer than winter, and the difference was significant(P<0.05). 【Conclusions】 Child's BMD of north china is increased with the actual month and correlate with gander and ages. Childs in adolescent should pay attention to take calcium and vitamin D. Child in summer and autumn should take appropriate amount vitamin D according to sunshine time.
    Time dependent of glutamate concentration in brain tissue of neonatal rats with hypoxic-ischemic brain damage
    LV Shi-shen, AN Li, WANG Ping, ZHENG Yuan
    2011, 19(8):  716-719. 
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    【Objective】 To investigate the time dependent manner of glutamate concentration in brain tissues of rodent model in different postnatal days and its intervention study. 【Methods】 Total 128 neonatal SD rats were divided into 4 groups according to postnatal days(P)∶P2, P6, P12, P18(n=32). Each group were randomly divided into 4 groups: hypoxic-ischemic brain damage(HIBD) group(H), α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate(AMPA) group(A), GYKI52466 group(G) and normal control group(N) (n=8). Standard HIBD models were set up according to Rice methods on rats of H, A, G groups. Rats of the A and G groups were injected drugs immediately after modeling. Brain tissue of all groups was collected to detect the glutamate concentration and observe the pathological changes. 【Results】 The results showed that there was a negative correlation between glutamate concentrations and postnatal ages (r=0.81, P<0.01). The glutamate concentration in brain tissues of P2 group was the maximum and was dramatically higher than those of P6 group, P12 group and P18 group, respectively[(670.2±139.4) μmol/gprot vs(576±139 )μmol/gprot,(670.2±139.4) μmol/gprot vs(441.9±114.9) μmol/gprot and(670.2±139.4) μmol/gprot vs(287.0±82.8) μmol/gprot, q=3.88,9.41,15.80,P<0.05 or 0.01]. The glutamate concentration in brain tissues of G group was the minimum and there were significant differences compared with those of A, H and N groups[(348.6±128.5) μmol/gprot vs(608.6±176.7) μmol/gprot, (348.6±128.5) μmol/gprot vs(554.2±206.2) μmol/gprot, (348.6±128.5) μmol/gprot vs(463.8±167.1) μmol/gprot, q=10.72,8.49,4.75,P<0.01]. Pathological changes were consistent with the changes of glutamate concentration in each group. 【Conclusions】 Glutamate concentration shows time dependent in brain tissue of different postnatal days represent to different developmental level of neonatal brain. There is a negative correlation between glutamate concentrations and postnatal days. Glutamate concentrations increase in HIBD cases and decrease with treatment of GYKI52466. Neuroprotective effect of GYKI52466 is more obvious in relative early stage of gestational age. Early intervention with GYKI52466 is expected to prevent and cure neonatal brain damage resulted from premature birth or asphyxia.
    Measurement and analysis on markers of bone metabolism in neonates
    WANG Ai-ping, TAO Na, LI Yang-fang, YANG Ru-wen, LIU Rong-jun, WU Yu-qin, SHEN Jin, ZHANG Yan
    2011, 19(8):  732-734. 
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    【Objective】 To explore characters of bone metabolism in neonates. 【Methods】 The concentrations of serum osteocalcin (OC), beta-crossLaps (β-CTx), calcium, parathyroid hormone (PTH) and 25-hydroxycholecalciferol [25(OH)D3] were measured in 30 appropriate for gestational age(AGA) term infants, 17 small for gestational age(SGA) term infants, 33 AGA preterm infants and 6 SGA preterm infants, and the data were statistically analyzed. 【Results】 The concentrations of serum OC in group of SGA term infant and AGA preterm infants were less than that in group of AGA term infant(P<0.05); The concentrations of serum β-CTx in group of AGA term infant was less than that in group of AGA preterm infant(P<0.05); The concentrations of serum calcium in group of SGA and AGA preterm infant was less than that in group of AGA term infant(P<0.05); The concentrations of serum PTH in group of AGA preterm infant was less than that in group of AGA and SGA term infant(P<0.05); The concentrations of serum 25(OH)D3 had no statistical difference in group of AGA term infant 、SGA term infant、AGA preterm infant and SGA preterm infant(P>0.05). 【Conclusions】 The SGA term infant, AGA and SGA preterm infant easily occur metabolic bone diseases, the supervisal in metabolic bone diseases for them should be strengthened, and Vitamin D difficiency rickets in AGA term infant should be paid attention to supervise too.
    Cross-sectional investigation on rickets of 150 preschoolers and analysis of the relation between 25(OH)D3 level and X-ray
    QU Jian-ping, YANG Shu-fen, YANG Tao, REN Li-hong, YAO Li, TIAN Zhi-liang, WANG Wei, ZHANG Xue-lian
    2011, 19(8):  734-736. 
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    【Objective】 To investigate the prevalence of rickets for the preschool children and the relation between 25(OH)D3 level and X-ray in rachitic patients. 【Methods】 On January 2010, physical examination, medical history collection, blood test and X ray film of left wrist were did in 150 preschoolers who were randomly selected among 5 kindergartens and 2 preschool classes in the city of Suihua, then the data were analysed. 【Results】 52 preschoolers were suffering from rickets among the 150 preschoolers. The prevalence of rickets was 34.6%, it was not related with gender and age. The 25-(OH)D3 level in the rickets group with X-ray change was lower than that in the control group, and there were significant differences. 【Conclusions】 Rickets is still existed in preschoolers, but all of them are mild; The survey of 150 preschool children show that preschoolers in Suihua generally have vitamin D deficiency and shortages; The lower 25(OH)D3 level, the more likely X-ray changes are happen.
    Mental health condition and early treatment of preschool children in Liwan district of Guangzhou
    YIN Qing-yun, HUANG You-qi, LI Han-qiu, YE Xiao-hong, DANG Ya-mei, ZHANG Shuang-chun, CHENG Dao-meng, XU Li-ping
    2011, 19(8):  737-739. 
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    【Objective】 To study the temperament traits and mental health condition of preschool children in Liwan district in Guangzhou, in order to give early intervention for those patients with mental health disorder. 【Methods】 Children of 8 kindergartens in Liwan were selected and investigated with the questionnaire of Chinese Preschool Children Temperament Scale (CPTS), with 2-phases epidemiological methods. Individual psychological treatment and drug therapy were given to the diagnosed cases. 【Results】 The main temperament types of preschool children in Liwan were easy type and intermediate-low type, temperament dimension showed that boys were more active and intense than girls.The prevalence rate of mental health disorder was 3.83%. Anxiety disorder, behavioral and developmental disorders were common among these patients. 【Conclusion】 Corresponding guides should be given to the parents and proper early intervention for given cases.
    Blood lead levels and the related risk factors among children between 2008 and 2009 in Hefei city
    PENG Mei-lin, HAO Jia-hu, SU Pu-yu, DING Jia-lan, XU Xiao-rong
    2011, 19(8):  740-742. 
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    【Objective】 To investigate the trend of blood lead level and its related risk factors among children in 2008 and 2009 in Hefei. 【Method】 Stratified clustered random sampling was used. A total of 3 394 children of 0~6 years old were investigated in 2008 and 2009, and the specimens were measured by multi-channel BH2100 atomic absorption spectrometry. 【Results】 The mean blood lead concentration of the boys and girls were respectively(47.06±23.30) μg/L、(45.09±23.30) μg/L. The blood lead levels of the boys in 1-year old group and 2-year old group both were significantly higher than that in other age groups. The girls in less than 0 age to 2 age groups were significantly higher than that in other age groups. Except Baohe and Gaoxin districts, the blood lead levels of children in other districts were significantly lower in 2009 than in 2008. The incidence of child's lead poisoning in 2009 was significantly lower than in 2008 overall the city. The following factors might serve as major risk factors related to child's lead poisoning, such as, father engaged in lead relevant professional, living in nearby highways (less than 30 meters), outdoor activity more than 3 hours, not washing hands before eating, and so on. 【Conclusion】 The blood lead levels of children in Hefei presented down a good situation, the publicity and education of poisoning hazards still should be strengthened and effective intervention measures on child also should be concerned and taken in to actions.
    Study on the relationship between the blood lead level and behavior problems in the preschool children aged 3~7 years old in Shunyi district
    LIU Ya-jing, JIA Mei-xiang, HE Ya-ping, WANG Xiu-yun, XIANG Zheng, CUI Wen-hong, LI Xue-ling, LIU Jian-hua, JI Wei-long
    2011, 19(8):  743-745. 
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    【Objective】 To observe blood lead level and distributed characteristics among children of 3~7 years old in Shunyi district in Beijing and to explore the effects of lead poisoning on preschool children behaviors. 【Methods】 1 307 children of 3~7 years old were investigated from April to June 2009. All subjects were selected from 5 kindergartens through a clustered-random sampling in Shunyi district.Blood lead level was measured and behavior problems were made by CBCL.All children were divided into 2 group(high blood lead group and low blood lead group)by blood lead beyond or below 100 μg/L .The behavior problems were identified while the total crude scores of CBCL beyond 42 in boys and 45 in girls. 【Results】 The geometric mean of blood lead was (3.328±2.765) with 1.22% of those ≥100 μg/L,and 0.15%≥200 μg/L.The median of CBCL total crude scores in high blood lead group was significantly higher than those of low blood lead group(P<0.001).The ratio of behavior problems in high blood lead group(76.47%) was significantly higher than that of low blood lead group(10.85%)(P<0.001).The ratios of behavior of attack, hyperactivity and disobey were significantly higher in high blood lead group than those of low blood lead group in boys(P<0.05). The ratio of behavior of disobey was significantly higher in high blood lead group than that of low blood lead group in girls(P<0.001). 【Conclusions】 Preschool children lead poisoning is associated with their behavior problems. Promoting healthy information can alleviate danger of high blood lead.
    Analysis on the relationship between gingivitis and permanent teeth caries among 12~13 year-old children in Guangzhou
    WANG Dong-mei, WANG Ping, LIANG Huan-you, WU Jian
    2011, 19(8):  746-748. 
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    【Objective】 To investigate the relationship between gingivitis and permanent teeth caries of children to provide theoretical basis for gingivitis prevention of children. 【Methods】 Multistage stratified cluster random sampling method was used to obtain 1115 samples among 12~13 year-old children in Guangzhou. The methods and criteria of gingivitis and caries were abided by World Health Organization in 1997. The examination indices of gingivitis and caries were scored with GI and DMFT, respectively. Logistic regression analysis was used to explore the relation between gingivitis and permanent teeth caries in 12~13 year-old children in Guangzhou. 【Results】 In the cohort aged 12~13, the prevalence of gingivitis was 72.65%. The prevalence of moderate and severe gingivitis was 28.16% and 5.83%, respectively. The prevalence of caries of the subjects was 25.83%, the non-filled tooth accounted for 73.73% among DMFT. The result of Logistic regression analysis showed non-filled caries was a risk factor of gingivitis in 12~13 year-old children in Guangzhou. 【Conclusion】 The children who had non-filled caries are focus on prevention of gingivitis in Guangzhou.
    Analysis of behavioral problems and related factors in school-age children with asthma
    YU Jie, WU Hui-fang, ZHAO Jian-mei, XU Mei-yu, ZHOU Hui, LI Hai-ying
    2011, 19(8):  749-751. 
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    【Objective】 To study the behavioral problems and related factors in school-age children with asthma. 【Methods】 Followed up 92 cases of school-age children with asthma, they were investigated with self edited general questionnaire and parents' chart of Rutter children's behavior questionnaire. 92 cases of healthy children were sampled as control group matched by age, sex etc, they also were investigated with parents' chart of Rutter children's behavior questionnaire. 【Results】 Among 50 cases of boys with asthma, 22 cases (44.00%) had behavioral problems, of which 19 cases (38.00%) had violation discipline and 15 cases (30.00%) had neurotic behavior. The rates were significantly higher those of control group(all P<0.05). Among 42 cases of girls with asthma, 17 cases (40.48%) had behavioral problems, of which 15 cases (35.71%) had neurotic behavior. Significantly differences were found between two female groups(P<0.05),but no significantly difference was found in two groups with violation discipline(χ2=0.454,P>0.500). Multiple step-wise regression analysis suggested that the factors increasing behavioral problems of school-age children with asthma included the patient's age, onset duration, the annual average onset frequency and days, the recurrent numbers, weight-for-age and the days and the amount of intravenous steroid.The factors reducing behavioral problems of school-age children with asthma involved the first onset age, the actual proportion of learning time and the daily mean duration of outdoors activity. 【Conclusions】 Behavioral problems are significantly prevalent in asthma and much attention should be paid to them.
    Eating problems and levels of serum minerals in children with autism
    ZHOU Chang-hong, YANG Hong-lei, KUANG Gui-fang, FU Ping
    2011, 19(8):  751-753. 
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    【Objective】 To investigate the eating behaviors and levels of serum Zn, Ca,Fe,Mg,Cu of autism children. 【Methods】 The caregivers of 67 autism children and 52 normal children were requested to complete a questionnaire,especially in the side of selection and acception new food. Atomic absorption spectrometry was used to test levels of serum Zn,Ca,Fe,Mg,Cu contents. 【Results】 The problems of eating behaviors in autism group were more than in the normal group. The rates of Zn, Fe or Ca deficiency were more serious in autism group than that in normal group. 【Conclusions】 The problems of eating behaviors and the deficiency of Zn, Fe or Ca among autisms is very serious. Pediatricians should give correct guidance to the caregivers to solve the eating behavior problems.
    Preschool potential development education research of multiple births
    CHENG Huai,CHEN Yong-xiang,ZHANG Jie,WANG Xiu-yun,CHEN Ning,JI Xiao-cheng
    2011, 19(8):  758-761. 
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    【Objective】 To explore the effect of the potential development preschool education on the development of Xi quintuplets born in Hebei Province, 2002. 【Methods】 Applying the individualized education in potential development based on “evaluation-guidance-development” interactive mode, the development of Xi quintuplets was accessed each semester and the test results were analyzed statistically. 【Results】 After 31-month potential development individualized education, the average development quotient of the quintuplets rose from 97(4.1 years old)to 115 at age 6, and an average rise of 19 percentages; the intervention effect was significant. The average IQ(CRT)of the quintuplets at age 6.3 years was 124.6; the IQ of two (one boy and one girl among them), reached over 130. 【Conclusions】 The development results of the quintuplets confirm our previous research results that the individualized education, assessing each sub-field of early childhood development, is a feasible and effective form of early education.
    Study on dental caries status in 3~6-year-old kindergarten children of Laoshan, Qingdao
    TANG Ai-ping, DU Ji-peng
    2011, 19(8):  763-764. 
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    【Objective】 To study the situation of dental caries in 3 to 6-year-old kindergarten children in Laoshan, Qingdao. 【Method】 Oral examinations were performed on 5 620 kindergarten children of Laoshan district which aged 3 to 6 years old and the dental caries data were analyzed by χ2 test. 【Results】 The prevalence of dental caries in children aged 3 to 6 years old was 27.7%. As for gender, the prevalence of dental caries was 26.9% for boys and 28.2% for girls. No significant difference in caries prevalence was found by gender. The caries prevalence of children was increased with age, which reached its highest as 49.56% in > 5~6 years old group. There was a significant difference in caries prevalence between age groups. 【Conclusions】 In order to prevent children from dental caries, oral hygiene measures and strategies must be carried out from early childhood when they have primary teeth. Reducing the caries prevalence in children needs cooperated efforts from both parents and kindergarten teachers.
    Evaluation on the effect of health interventions for under-five children in targeted rural areas of Shaanxi province
    ZHOU Jing-ya, LIU Fen, LI Tao, REN Shan-shan, JU Li-rong
    2011, 19(8):  769-771. 
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    【Objective】 To evaluate the effect of integrated health-care interventions for children under 5 years old in target rural counties of Shaanxi Province and to provide experiences and lessons for following projects. 【Methods】 From 2007 to 2010, a project focusing on maternal and child health care was launched in targeted rural areas of Shaanxi Province, with integrated interventions. Together with using multistage, stratified, randomly, non-probability sampling, two cross-sectional surveys were conducted in 2006 and 2010, and a before/after intervention design was used to assess the effectiveness of the integrated interventions by changes in children's growth and development, health outcome, guardians' health-related knowledge and behavior. 【Results】 The decrease in the stunting rate was more than 50% after intervention(6.9% to 3.4%, P<0.01). The rate of anemia was still high and also little effect had been shown in reduction of both two-week prevalence of suspected pneumonia and two-week prevalence of diarrhea(P>0.05). However, there was significant improvement in health awareness and behavior among caregivers, especially the rate of professional care-seeking when either of the disease occurred increased dramatically to more than 85%. 【Conclusions】 This project, to some extent, has promoted the health of children under 5 and the level of health care, but little effect showed in the reduction of anemia, suspected pneumonia and diarrhea. So it is still urgent to seek more specific and targeted interventions fighting against such problems and to improve intensity of interventions as well.
    Research and application of information technology in the neonatal screening field
    QIU Lei, DING Hui, ZHANG Yu-min, KONG Yuan-yuan, YANG Hai-he, PAN Ying
    2011, 19(8):  772-774. 
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    【Objective】 In order to improve the service and management level of the neonatal screening work, pull the modern information technology into this field. 【Methods】 The "Beijing neonatal screening information management system" were designed which was based on the Hanxin code and on the basis of Beijing maternal and children information network. 【Results】 Neonatal screening information system could screen samples from the new collection, delivery, laboratory tests, to recall suspected cases, diagnosis, treatment, follow-up the whole process of information, which had a good supporting management and public inquiries function. 【Conclusion】 It is necessary and advantageous to build a new screening information management system, which can optimize the new screen business processes, improve the management level.