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    10 September 2017, Volume 25 Issue 9
    Functional enuresis in developmental and behavioral pediatrics
    MA Jun,JIN Xing-ming
    2017, 25(9):  865-864.  DOI: 10.11852/zgetbjzz2017-25-09-01
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    Functional enuresis is a typical elimination disorder in developmental and behavioral pediatrics,which is hard to treat and easy to relapse.It is emphasized that clinically stereoscopic evaluation is essential to identify the effective interventions.It is only on the basis of an accurate evaluation,functional enuresis might be cured,and must be taken the model of management of chronic diseases into account.As such,enuresis and its functional impairments could be controlled.
    Validity and reliability of the Family Functioning Assessment Scale for Children
    LUAN Feng-huan,DU Ya-song,ZHONG Xiang-yang,LI Meng-yao,ZHOU Hui-ming,CHENG Yong-chen
    2017, 25(9):  868-867.  DOI: 10.11852/zgetbjzz2017-25-09-02
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    Objective To test the reliability and validity of the Family Functioning Assessment Scale for Children (FFAS-C).Methods A total of 2 931 children aged 7~12 years old in Shanghai were selected and stratified by age and grade as the main variables.All children filled out FFAS-C,their parents completed the Family Function Device-the General Function (GF).FFAS-C was retested with the same procedure after 255 days of interval.Results The Cronbach's α coefficient of FFAS-C was 0.808,and the internal consistency reliability coefficient of each dimension was between 0.603 and 0.729.The Pearson correlation coefficient of each item and the total score was between 0.431 and 0.607 (P<0.01).Spearman-Brown half confidence coefficient was 0.822,Guttman half confidence was 0.815,the retest correlation coefficient was 0.74 (P<0.01).The results of exploratory factor analysis showed that FFAS-C could be divided into three factors,which were verified by confirmatory factor analysis.The high-score group of GF was higher than those of score group-low of GF in the total score and each dimension score of FFAS-C (P<0.01).Conclusion The FFAS-C has good reliability and validity.
    Research on reliability,validity and clinical application of the initial sensory profile (0~3 years)
    HE Yan-lu,YANG Zhi-yong,OU Jia-xin,WANG Jing,CHI Xia,TONG Mei-ling,XU Guang-xu
    2017, 25(9):  872-871.  DOI: 10.11852/zgetbjzz2017-25-09-03
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    Objective To analyze the reliability and validity of the sensory profile (0~3 years) and the ability of infants/toddlers sensory processing.Methods A total of 378 children's caregivers completed the sensory profile to evaluate the reliability,validity and the ability of sensory processing.Results The Cronbach's α coefficient for both sections (0~6 months and 7~36 months) of the sensory profile were 0.720 and 0.871.The test-retest reliability was 0.659.The Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy were 0.646 and 0.772.Using principal component analysis (pca),all dimensions were within the acceptable range,the correlation coefficient between total score and each item score ranged from 0.371 to 0.856.The rate of definite difference of sensory processing sections was 2.4%~13.2%.The rate of definite difference of sensory profile quadrants was 4.0%~11.7%.Conclusions The reliability and validity of the sensory profile is satisfactory and the results are consistent with the English version of the scale.It can be further studied and applied in clinic.
    Analysis of the risk factors in Uighur children with cerebral palsy in Xinjiang
    YU Jing,TANG Jiu-Lai
    2017, 25(9):  876-875.  DOI: 10.11852/zgetbjzz2017-25-09-04
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    Objective To analyze the risk factors in Uighur children with cerebral palsy (CP) in Xinjiang,and to provide clinical evidence to the prevention and treatment of CP.Methods A total of 286 Uighur children with CP and 572 healthy Uighur children (0~6 years old) were collected from Xinjiang autonomous region people's hospital during Jan.2013 to Jun.2015.The risk factors of CP was analyzed by single factor and multiple-factor logistic analysis method.Results Single factor logistic analysis showed that the incidence of CP correlated with genetic factor and various antenatal,intrapartum and postpartum factors.Multiple-factor logistic analysis showed that the risk factors of CP mainly contained intermarriage,family history of encephalopathy,pregnant infection,negative reproductive history,gestational age <32 weeks,fetal distress,low birth weight,neonatal asphyxia,neonatal severe jaundice and newborn hypoxia ischemia.Conclusions The incidence of CP for Xinjiang Uighur children is related to multiple risk factors,the prevention and intervention of each risk factors should be strengthened to reduce the incidence of CP in children.
    Mediating and moderating role of resilience between Machiavellianism and problem about depression,anxiety and stress among kiddies
    YANG Zi-hao,GENG Yao-guo,YAN Feng-yan,ZHANG Rui-xing,GUO Wei-wei,WANG Cong-dan
    2017, 25(9):  879-878.  DOI: 10.11852/zgetbjzz2017-25-09-05
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    Objective To investigate the relationships among Machiavellianism,problems about depression,anxiety and stress and resilience in kiddies in order to explore the actual processes that Machiavellianism affect problems about depression,anxiety and stress.Methods A total of 6 401 kiddies from middle and primary schools in Zhengzhou and Hong Kong participated in the study.Students were sampled to fill out the Kiddie Machiavellianism Scale,the Depression Anxiety Stress Scale,and Resilience Scale.Statistical methods included independent sample t test,Pearson correlation analysis and hierarchical regression analysis.Results 1) Resilience partially mediated the effect of Machiavellianism on problems about depression,anxiety and stress,and the mediating effect occupied 46% of the total effects.2) Resilience also moderated the relationship between Machiavellianism and problems about depression,anxiety and stress.Conclusiond Machiavellianism not only directly predict children's problems about depression,anxiety and stress,but also makes children face more these problems by weakening resilience.In addition,resilience can reduce the negative impact of Machiavellianism on problems about depression,anxiety and stress,which has a protective effect on children's mental health.
    Effect of childhood psychological maltreatment on memory bias among middle school students from rural area
    SONG Rui,LIU Ai-shu,HAO Bing-hui,TONG Xin,AN Chun-ping,NING Shi-ying
    2017, 25(9):  883-882.  DOI: 10.11852/zgetbjzz2017-25-09-06
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    Objective To analyse possible memory bias among middle school students from rural area with childhood history of psychological maltreatment.Methods A total of 25 students with psychological maltreatment and 27 students without psychological maltreatment were selected to participate in the self-referent encoding task experiment.The 2 groups (psychologically maltreatment group/ control group) ×2 stability of adjectives (trait/ state) ×2 nature of adjectives (negative/ positive) mixed-design experiment was conducted to investigate the impact of childhood psychological maltreatment on memory bias.Results 1)ANOVA results showed the main effect for adjectives nature was significant (P<0.001),groups × nature had a significant interaction effect (P<0.05).2)The SRET's reaction time showed:the main effect for adjectives stability was significant (P<0.05),groups × nature had a significant interaction effect (P<0.001).3) The result of SRET's recall test showed:groups × nature had a significant interaction effect (P<0.001),groups × nature× stability had a significant interaction effect (P<0.05).4) The positive reaction bias of maltreatmented group was significantly lower than that of controlled group (P<0.05).Conclusion Junior high school students who were experienced psychological maltreatment in childhood may have memory bias to negative self-related information.
    Effect of long-term oral use of glucocorticoid on mood and mental state of children with chronic illness
    ZHANG Yan,SUN Jing,LIAN Dong-mei,LIU Ao-bo,XIANG Na,LI Yang
    2017, 25(9):  887-886.  DOI: 10.11852/zgetbjzz2017-25-09-07
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    Objective To analyse the influence of long-term oral use of glucocorticoid on mood and mental state of children with chronic disease.Method Totally 140 children with chronic illness aged from 10 to 18 were selected by convenience sampling to finish the self-designed questionnaire,Piers-Harris Children's Self-concept Scale(PHCSS) and Depression Self-Rating Scale for Children (DSRSC).Multiple hierarchical regression analysis was used to explore the effect of extended oral glucocorticoid on mood and mental state of participants.Results The average score of self-concept scale and depression scale were 55.50±11.49 and 9.11±4.81 respectively.29.0%children reported low level of self-concept(<50 scores)and 15.9% children were with high level of depression.The results of hierarchical regression analysis showed that the long-term oral use of glucocorticoid could explain 5.6% of the variance in self-concept and 3.1% in depression.Conclusion Long-term oral use of glucocorticoid could influence the mood and mental state of children with chronic disease,who are prone to appear low level of self-evaluation and depression disorder.
    Effect of children's sling exercise training system on trunk control and gross motor function in children with cerebral palsy
    KANG Bei-bei,XU Lei,LU Ming-jia,PANG Wei,JIANG Zhi-mei,XU Qiu-xia
    2017, 25(9):  891-890.  DOI: 10.11852/zgetbjzz2017-25-09-08
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    Objective To observe the effect of children 's sling exercise training system on trunk control and gross motor function in children with cerebral palsy.Methods Totally 40 children with spastic cerebral palsy were randomly divided into two groups.The control group (n=20) was treated with routine rehabilitation training.The observation group (n=20) was treated with routine rehabilitation training and the children's sling exercise training system.The two groups were assessed with Berg Balance Scale (BBS) and 10 cm mass walking speed (MWS) on the trunk control and walking ability before and after treatment.The Gross Motor Function Measurement (GMFM) was used to evaluate gross motor.Results The BBS score,10 m MWS and GMFM scores of the two groups after treatment were significantly different from those before treatment (all P<0.05).And the score of the observation group was significantly higher than that of the control group (P<0.05 ).Conclusion The children's sling exercise training system can effectively improve the trunk control ability and gross motor function of children with spastic cerebral palsy.
    Autistic screening and three-year follow-up study of autistic warning indicators
    WEI Rong-mei,LIU Zhi-mei,ZHANG Lan,ZHAO Ting,BU Ru,CHEN Xue-zhen,WANG-Lei
    2017, 25(9):  894-893.  DOI: 10.11852/zgetbjzz2017-25-09-09
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    Objective To investigate the outcomes and prognosis of autistic children by follow-up visiting children with positive autism caution index (CI) within 1 year for 3 years.Methods In the high-risk outpatient department,the follow-up examination,family intervention guidance,regular evaluation and 3-year follow-up visiting were conducted in the children with positive autism alert index according to the Autism Diagnosis and Rehabilitation Guide issued by the Ministry of Health in 2010.The Children Autism Rating Scale (CARS) and the Gesell Development Scale were tested in the children with autism (experimental group) and the random outpatient children at the same age (control group),and result of each group were analyzed.Results 30 autism spectrum disorders were diagnosed out of 35 high-risk patients,and 5 were diagnosed with others including 2 cases of mental retardation,1 case of congenital pigment incontinence,1 case of tuberous sclerosis,1 case of congenital blind child.The CARS score of the ASD children was lower than that of the control group (P<0.001).The Gesell development scale test showed that the children with ASD had a higher CARS score than the control group (P<0.001).The five energy levels of the two groups were both lower than normality,but each energy level of the control group was lower than that of the experimental group (P<0.001).Conclusion It is feasible to use infant early warning indicators of autism spectrum disorders to screen children with autism early,which is helpful to reduce the severity of autism and to improve the ability of autistic children.
    Experimental study on recognizing facial expression with different intensities in children with autism spectrum disorder
    WANG Lei,FENG Jian-xin,FAN Yong
    2017, 25(9):  897-896.  DOI: 10.11852/zgetbjzz2017-25-09-10
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    Objective To analyse facial recognition abilities and features of students with autism spectrum disorder under different intensity levels.Method A total of 15 children with high-functioning autism spectrum disorders and 15 biological age matched normal children were selected,to find face expression recognition characteristics of autism and effects of expression intensity.Result 1)The abilities of facial expression recagnition in children with autism spectrum disorder is significantly lower than that of normal children was score of identifying positive emotion was better than that of negative emotion;2)Medium level emotion recognition was faster than the low and high varying intensity,but the accuracy of high level of emotion recognition was better than that of low and medium level of emotion recognition.Conclusions 1)Autism have defects in facial expression recognition.2)Expression intensity affects facial expression recognition in ASD children Greater intensity of expression,better performance will make expression coding more effective,so that expression is more likely to be discerned for autism.
    Effects and potential mechanisms of congenital lead exposure on interdigestie migrating motor complex changes of stomach,duodenum and jejunum in offspring rats
    ZHOU Jian-ping,WANG Fan,WANG Jing-jing,JIANG Yong-sheng,GENG Yan,WANG Xue-ying,ZHONG Bo
    2017, 25(9):  900-899.  DOI: 10.11852/zgetbjzz2017-25-09-11
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    Objective To analyze the effect and potential mechanisms of congenital lead poisoning on interdigestove migrating motor complex (IMMC) changes of stomach,duodenum and jejunum in offspring rats.Method The animal model of congenital lead exposure was established with pregnant rats drinking freely 0.1% (low-dose group,LG) and 0.2% (high-dose group,HG) lead acetate solution.The normal control group (NG) was also established.IMMC changes of stomach,duodenum and jejunum of male offspring rats were observed in technique of electrophysiological monitor.The methods of immunohistochemistry and radioimmunoassay were also applied to elucidate the potential mechanism of gastrointestinal (GI) motility disorders in the plasma levels and GI tissue expressions of CCK-8 and MTL.Results Compared with group NG,the periods and amplitudes of GI IMMC Ⅲ phase increased (P<0.01) in the offspring rats with lead exposure in embryo period.Furthermore,the increase of CCK-8 expressions and decreasing MTL expressions in gastric antrum mucosa (P<0.01),increasing expressions of CCK-8 and MTL in proximal duodenal mucosa (P<0.01),and as well as increasing levels of plasma CCK and MTL (P<0.01) were observed in groups LG and HG.The differences among these three groups were of statistical significance (P<0.01).Conclusions The abnormal changes of GI motility are observed in offspring rats with lead exposure in embryo period.It is possible that the different expressions or distribution of CCK and MTL in the peripheral tissue and blood are the important mechanisms for these pathological changes.
    New advances in the treatment of autism spectrum disorders
    CAO Juan,CHEN Yi-xin
    2017, 25(9):  904-903.  DOI: 10.11852/zgetbjzz2017-25-09-12
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    Nowadays,comprehensive education and training is advocated in the treatment of autism spectrum disorder.Music therapy is one of the auxiliary measures.Some studies show that it can enhance the children's social interaction,lift their spirit and promote their overall development.This paper briefly reviews the progress of domestic and overseas researches on the application of music therapy in the treatment of children with autism spectrum disorder.
    Progress of transcranial magnetic stimulation in treatment of autism spectrum disorder
    ZHAO Qin,SHAO Zhi
    2017, 25(9):  907-906.  DOI: 10.11852/zgetbjzz2017-25-09-13
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    Autism spectrum disorder(ASD) has been cited as a group of developmental disabilities with serious consequences.Recent studies indicated abnormalities in cortical minicolumn might be the core neuropathological mechanism for ASD.Transcranial magnetic stimulation could improve the manifestations of patients with ASD by targeting abnormal minicolumns,changing the local cortical excitability,and rebalancing the ratio of cortical excitation to inhibition.This article reviews recent researches about using transcranial magnetic stimulation in treatment of ASD,and discusses its future development in this area.
    Progress in diagnosis and treatment of hyperbilirubinemia in premature infants
    HUANG Jia,WU Yun-qin,GAO Xi-rong
    2017, 25(9):  910-909.  DOI: 10.11852/zgetbjzz2017-25-09-14
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    Preterm born with a high proportion of fetal red blood cells would have,a large number of early fetal red blood cell damaged,and increased bilirubin source.Moreover preterms liver function is immature.And its poor intake,utitization and excretion of bilirubin dysfunction,makes preterms prone to hyperbilirubinemia.For neonates with gestational age over 35 weeks,the corresponding phototherapy curve and the hourly bilirubin line chart have been used as diagnostic or intervention criteria.However preterm infants with gestational age less than 35 weeks still lack an accepted intervention guideline.This article reviews the latest diagnosis and treatment of hyperbilirubinemia in premature infants.
    Pathogenesis of effects of exposure to atmospheric pollutants during pregnancy on infant allergic diseases
    CHEN Zhen-jiang,GU Gui-xiong,HUA Jing
    2017, 25(9):  914-913.  DOI: 10.11852/zgetbjzz2017-25-09-15
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    The pregnant period is the most important one in our whole life.According to the literature in western countries,the allergic diseases may be induced by the air pollution which could mediated by the fetal developmental programming.Therefore,this article review the pathogensis and correlation between exposure to air pollutants and allergic diseases,in order to provide clues for the prevention and treatment of these diseases.
    Research progress on program for the Education & Enrichment of Relational Skills to the improvement of social skills in teens with autism spectrum disorder
    LI Gai-zhi,DU Ya-song
    2017, 25(9):  917-916.  DOI: 10.11852/zgetbjzz2017-25-09-16
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    Autism spectrum disorder is mainly characterized by social deficit,especially in teens.The related training program is seriously needed in China.Program for the Education & Enrichment of Relational Skills (PEERS<img src='R.JPG'/>) is evidence-based practice for teens with social deficit.The overview and research progress on PEERS are described in this paper.
    Status and risk factors for parenting behavior of infants from rural areas in southern Shaanxi province,China
    YUE Ai,ZHANG Nian-rui,LI Liang-liang,LI Shan-shan,LUO Ren-fu,SHI Yao-jiang
    2017, 25(9):  921-920.  DOI: 10.11852/zgetbjzz2017-25-09-17
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    Objective To investigate the situation of parenting behavior and related risk factors of infants aged 18~30 months from rural areas in southern Shaanxi province.Methods A total of 1 243 infants and their families from rural areas of southern Shaanxi province,China were enroulled in this study.Multivariate regression analysis and t-test were performed to determine the risk factors for the parenting behavior in caregivers.Results 1)The mother was the primary caregiver for 67.34% of the children in the sample.For these infants,10.62% of the mothers had completed fewer than 9 years of schooling;2) 13.68% of caregivers read to their children.Similarly,38.37% of caregivers sang to their children on the day prior to survey administration.39.9% of parents used toys to play with their children on the day prior to survey administration.Most sample households (90%) spank the infants sometimes or often.3) Multivariate regression analysis showed that caregivers' education,access to internet and telephones,and the assets of household have significant impact on the parenting behavior(P<0.01).Conclusion Improving the education and access to internet in rural area can decrease the risk of development in infants.
    Study on the changes of parameter of peripheral blood leucocytes in physical examination of children
    ZHANG Lei,DUAN Xiao-jing,WANG Jin-hua,ZHANG Yan-ping,HUANG Lun,ZHANG Wen
    2017, 25(9):  925-924.  DOI: 10.11852/zgetbjzz2017-25-09-18
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    Objective To analyze the morphological parameters of peripheral blood leucocytes in children,and to find the clinical significance.Methods A total of 180 healthy children (under 15 years old) were enrolled in this study,and parameters of white blood cells were analyzed by Sysmex XE-2100 automatic blood analyzer.The parameter data and changes of white blood cells were analyzed by age 0~,1~,2~,6~,12~15 years old.Results The fluorescence of neutrophilic granulocytes (NEUT-X) of all age groups were 1 355.0±41.5,1 348.3±22.5,1 348.4±51.3,1 339.3±51.6,1 335.8±46.2 respectively,and there were no statistical difference among groups (P=0.292).The fluorescence intensity of neutrophilic nucleic acid (NEUT-Y) were 495.6±28.2,477.6±38.6,486.5±40.2,481.3±32.2,479.9±39.6 respectively,and there were no statistical differences (P=0.412).The fluorescence intensity of lymphocyte nucleic acid (LYMPH-Y) were 713.6±46.3,708.3±60.3,711.0±61.2,712.8±72.3,711.6±75.3,and there were no significiant differences among groups (P=0.115).The fluorescence intensity of lymphocyte(LYMPH-X) were 896.3±36.2,854.6±19.3,858.4±17.6,860.1±15.7,851.3±18.2,and there were statistical differences among groups (P=0.008).Conclusion The granularity of peripheral blood lymphocyte in healthy children under 1 year old is higher than that of other ages,which indicated 0~1 years old children have better immunity.
    Comparative study on intelligence structure between school-age children with Asperger syndrome and attention deficit hyperactivity disorder
    LIANG Ya-yong,CHEN Kai-yun,CHEN Bi-yuan,CEN Chao-qun,ZOU Xiao-bing
    2017, 25(9):  928-927.  DOI: 10.11852/zgetbjzz2017-25-09-19
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    Objective To analyse the difference of intelligence structure between Asperger syndrome (AS) children and attention deficit hyperactivity disorder (ADHD) children in school-age.Methods A total of 157 school-age AS children(146 males and 11 females,aged from 6 to 14 years,with an average age of 8.47±2.07 years) and 157 school-age ADHD children(145 males and 12 females,aged 6.1 to 14 years,mean 8.81±1.66 years) were evaluated by the Wechsler Intelligence Scale (C-WISC) .The test results of the two groups were compared and analyzed.Results 1)The ratio of verbal intelligence quotient (VIQ) > performance intelligence quotient (PIQ) in AS group (40.76%) was significantly higher than that in ADHD group (9.55%).And the ratio of PIQ>VIQ in ADHD group (19.11%) was significantly higher than that in AS group (5.73%).The imbalance of intelligence development between the two groups ("VIQ-PIQ>14" and "PIQ-VIQ>14") was different (P<0.01).The ratio of intelligence development imbalance in AS group (46.50%) was significantly higher than that in ADHD group(28.66%)(P<0.01).2)Kaufman factor analysis showed that there was no significant difference between the two group in memory and care factor (C factor)(P>0.05) .But AS group had significantly higher score on Verbal Comprehension than that of ADHD group,and significantly lower score on Perceptual Organization than that of ADHD group,the differences were statistically significant (all P<0.05).Conclusions The intelligence development imbalance in school-age AS children is more common than that in ADHD children. AS children mostly have higher score on VIQ than PIQ ,whereas ADHD children have the opposite results.
    Comparison of response to name between autism spectrum disorder children and healty children aged 2~3 years old
    CHEN Xiao-yan,WU Jie-ling,LI Ming,LIU Wen-bo,ZOU Xiao-bing
    2017, 25(9):  931-930.  DOI: 10.11852/zgetbjzz2017-25-09-20
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    Objective To explore the objectivity differences of responses to name between autism spectrum disorder (ASD) and children with normal development.Method A total of 22 ASD children diagnosed in Children Development & Behavioral Center of the Third Affiliated Hospital of SUN Yat-sen University from May to August in 2016 and 21 controls was enrolled in this study.In standard procedure testing the response to name.After that,two professional evaluators scored the response to name,and automatic system computational analyzed the time of response to name and duration to response.Result 1)There were no significant differences in scores of response to name between ASD children and normal children (Z=15.764,P<0.01).2)The computational analysis showed that in response to name procedure,the response time showed no differences in ASD group and control group (Z=-1.593,P=0.113),But response duration was shorter in ASD group than that in control group(Z=-3.4,P=0.001).Conclusions Compared to normal children,2~3-year-old children with ASD have inferior behavior in response to name.The characteristics of abnormal response to name in ASD children include less eye contact and shorter response duration.
    Correlation study of fundamental movement skill development and related influencing factors in primary school children
    WU Hua,RUAN Hui,ZHANG Xin-ding
    2017, 25(9):  935-934.  DOI: 10.11852/zgetbjzz2017-25-09-21
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    Objective To analyse the relationship among fundamental movement skill,body mass index and functional movement in primary school children,and to provide theoretical and experimental basis for promoting the development of children's motor skills.Methods TGMD-2 was conducted on 240 school-age children to assess their fundamental movement skill development level.Children were divided into different groups by BMI and FMS test,and the characteristics and correlation of fundamental movement skill,BMI and FMS ability were compared between different groups.Results 1) There was still a certain gap to maturity level of fundamental movement skill; 2) There was no significant correlation among TGMD total score,object control score and BMI.Negative correlation not only existed between locomotion subjects score and BMI but also between FMS score and BMI; 3) TGMD scores and FMS scores showed significantly positive correlation,indicating TGMD score highly depended on FMS test results.Conclusion The development of children's motor skills requires a systematic scientific training process.
    Effects of pregnancy hypertension in mother on premature outcome
    YANG Chun-yan,TIAN Min,XU Ping,LI Bao-yun,YANG Qiao-zhi
    2017, 25(9):  938-937.  DOI: 10.11852/zgetbjzz2017-25-09-22
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    Objective To investigate the effect of gestational hypertension on the outcome of premature infants,and to provide a scientific basis for clinical diagnosis and treatment.Methods Totally 112 cases admitted to NICU were enrolled in observation group from January to December 2015.Meanwhile,a total of 102 cases with fetal distress premature were selected as the control group.Complete clinical data including the general data,white blood cells,hemoglobin,platelet,coagulation function,related complications and other data were collected and compared between two groups.Results In observation group,the gestational age and the ratio of low birth weight newborn were lower and the difference was significant.There were difference between gestational age and the ratio of were not statistical.In observation group,antenatal abnormalities (intrauterine distress,amniotic fluid pollution) and sepsis cases after birth were significantly higher.In observation group,the levels of white blood cells,platelets,and number of neutrophils were lower than control group and PT,APTT were higher than control group.In observation group,the respiratoy support time and oxygen time were significantly longer than in control group.And the incidence of retinopathy of prematurity (ROP),necrotizing enterocolitis (NEC) and intracranial hemorrhage(IVH) was higher which difference were significant.The NBNA in the observation group were significantly lower than those in the control group (P<0.05).Conclusions Gestational hypertension may cause fetal intrauterine growth restriction.Pretmature infants born to gestational hypertension mothers are prone to high incidence of leukocytopenia,neutroperia,coagulation disorder,infection,sepsis,comorbidity and sequela.
    Clinical observation of botulinum toxin injection with propofol anesthesia in the treatment of infantile spastic cerebral palsy
    LI Yan-hui
    2017, 25(9):  942-941.  DOI: 10.11852/zgetbjzz2017-25-09-23
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    Objective To observe the analgesic effect of botulinum toxin injection under propofol anesthesia in the treatment of children with spastic cerebral palsy.Methods Children with cerebral palsy admitted in hospital from January 2014 to December 2015 were randomly divided into observation group (propofol anesthesia botulinum toxin injection group) and control group (botulinum toxin injection alone),the routine rehabilitation training after injection;heart rate,respiration,systolic blood pressure,percutaneous oxygen saturation during the injection to judge.Patient compliance were evaluated at 1,3 and 6 months after treatment by the Modified Ashworth Scale (MAS),Gross Motor Function Scale (GMFM) .Results A total of 76 patients were eligible.The difference of heart rate and systolic blood pressure in the control group were significantly (P<0.05).The heart rate of the control group was significantly faster than that of the observation group.There was no significant difference about the percutaneous oxygen saturation between the two groups;the treatment group did not appear respiratory depression.The scores of MAS and GMFM between the observation group and the control group were significantly different (P<0.05) at each time point after treatment,and there was no significant difference between the two groups after the treatment in March and June;The MAS and GMFM scores in the same time between the observation group and the control group were not statistically significantly different.The score of MAS in the observation group is lower than that in the control group,and the score of GMFM is higher than that of the control group.The rate of re-injection was 98% in the observation group and 70% in the control group.There was significant different between the two groups.Conclusions Propofol is an effective and safe analgesic,safe and easy to use.It is very important to manage analgesic in children with cerebral palsy by receiving botulinum toxin injection.
    Study on the correlation of C-peptide,insulin,cortisol with neonatal hypoglycemia
    ZHAO Jin-zhang,LIU Ling,ZHANG Li,GUO Jin-zhen,LI Zhan-kui
    2017, 25(9):  945-944.  DOI: 10.11852/zgetbjzz2017-25-09-24
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    Objective To analyze the correlation of C-peptide,insulin,cortisol with neonatal hypoglycemia.Methods Totally 258 cases of newborns with hypoglycemia admitted to hospital from January 2015 to February 2016 were selected as the research objects.Another 80 cases of newborns with normal blood glucose were selected as contrast group.C-peptide,insulin and cortisol level were compared between the hypoglycemia group and the normal group to analyze the correlation of C-peptide,insulin,cortisol level,hypoglycemia duration time with hypoglycemia value.Results The levels of C-peptide and insulin of newborns in the hypoglycemia group were higher than those of the normal group,and the cortisol level was significantly lower than that of the normal group (P<0.05).C-peptide,insulin and hypoglycemia duration were positively correlated (r=0.748,0.814,all P<0.001);Cortisol levels were negatively correlated with duration of hypoglycemia (r=-0.809,P<0.001).There was a positive correlation between the values of C- peptide,insulin and hypoglycemia (r=0.832,0.786,all P<0.001) and cortisol level was negatively correlated with the values of hypoglycemia (r=-0.623,P<0.001).Conclusions The occurrence of neonatal hypoglycemia correlate with C-peptide,insulin,and cortisol.For newborns with abnormal levels of C-peptide,insulin and cortisol,special attention should be paid to prevent hypoglycemia though the test of hypoglycemia is normal so as to decrease misdiagnosis and to reduce the incidence of neonatal hypoglycemia sequelae.
    Research of the relationship between preschool children's nutrition and family eating behavior
    CHEN Gui-xia,TAN Jian-hui,ZENG Guo-zhang,YANG Mei-feng,SUN Xiao-ling,ZHANG Wei,WU Xing-dong
    2017, 25(9):  948-947.  DOI: 10.11852/zgetbjzz2017-25-09-25
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    Objective To analyze the relationship between nutritional status and family eating behavior in urban and rural preschool children.Method A total of 352 preschool children were selected from 3 kindergartens of urban and rural district in Xiamen,and were evaluated for body weight and height,nutrition status and family eating behavior by questionnaire survey.SPSS 22.0 software was used to analyze data.Results Preschool children's nutritional status:the incidence of children overweight obesity and growth retardation were 8.24% (29/352),3.13% (11/352) and 0.85%(3/352),respectivelly.45.5%(132/352)children's height were lower than medium height.Linear regression showed that birth height,parents' height,fish eating,average income were significantly associated with height-for-age(P<0.05).Children's weight-for-age was positively associated with birth weight and father's weight (P<0.01).Spearman correlation analysis showed height of children from city was higher that those in rural children.Children's BMI linear regression analysis indicated that quicker dine speed,more time on playing electronic products,expecting kids eating more,the more regarding overweight as healthy,then the higher the children's body mass index (BMI).Conclusion Long-term monitoring children's growth nutrition and eating behavior,as well as taking positive intervention targeting the problem,will help the healthy growth of preschool children.
    Retrospective analysis of drug resistance of mycoplasma pneumoniae infection in children
    FU Xiao-yan,QIN Xuan-guang,XIN De-li
    2017, 25(9):  951-950.  DOI: 10.11852/zgetbjzz2017-25-09-26
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    Objective To investigate the prevalence and mecharism of drug resistance of mycoplasma pneumoniae (MP) of children in Beijing area in 2015-2016.Method A total of 89 respiratory throat swab specimens were collected from children with fever,cough or sore throat and other respiratory tract infection symptoms,admitted in Beijing Chaoyang Hospital Affiliated to Capital Medical University in 2015-2016.These cases were assayed mycoplasma culture and drug sensitivity test and were amplified by nested PCR method for identification of MP resistance loci.Results 53 cases were positive of mycoplasma pneumonia,with infection rate of 59%.18 cases were sensitive strains and drug resistance rate was 66%.32 strains showed A2063G point mutation in 23S rRNA domain V district.Both A2063G and A2064G point mutation existed in 3 cases.Conclusions Mycoplasma pneumoniae infection rate in Beijing area is prevalent.The macrolide resistance rate is rising and the main resistance mechanism is 23S rRNA domain V point mutation.
    Physical health investigation of the unattended children in the garden in Chayuan area,Nanan district,Chongqing
    YU Chang-ying,CHEN Hong-xing,WANG Wu-xi
    2017, 25(9):  954-953.  DOI: 10.11852/zgetbjzz2017-25-09-27
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    Objectives To study the physical development of children in the garden in Chongqing Chayuan area in rural-urban fringe zone,and to find out the growth development problem in unattended children and common children to provide the basis for government decision-making.Methods A method of stratified cluster sampling were adopted to investigate 1 921 children in 17 level 3 gardens,including 958 unattended children and 963 common children.Based on WHO child growth standards(2006),comparison was made in height,weight,dental caries,ametropia and anemia detection rate of the two which described by constituent ratio.Results The Obesity and Ametropia detectable rates of the unattended children were 5.22% and 4.18%,which was statistically lower than the common children(7.58% and 8.93%).The other health indicators were not statistically different.Conclusion The unattended children in this area are in good physical health in the mass,mean while,the detection rate of dental caries is growing with children ages which more attention are needed.
    Analysis of mycoplasma pneumoniae infection in lower respiratory tract infections in children in Kunming from 2011 to 2015
    ZHAO Lin,CAO Li-yun,ZHAO Meng-ru,LIU Xu,LV Gao-jie,LI Ming-pan
    2017, 25(9):  957-956.  DOI: 10.11852/zgetbjzz2017-25-09-28
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    Objective To analyze the prevalence of mycoplasma pneumoniae infection in children with lower respiratory tract and to provide scientific basis for clinical diagnosis and treatment.Methods Pediatric clinical data and sputum pneumonia mycoplasma DNA-PCR were collected retrospectively from January 2011 to December 2015 in the Second Affiliated Hospital of Kunming Medical University and Kunming Maternal and Child Health Hospital.Results Among 8 433 cases of sputum detection,738 cases were positive of mycoplasma pneumoniae with average detection rate of 8.8%.The detection rate were 7.9%,8.1%,7.7%,9.9% and 9.6% respectively from 2011 to 2015.The detection rates of infant group,toddler group,preschool group,and school age group were 5.6%,9.7%,17.8% and 25.1%,respectively,The detection rates of spring,summer,autumn and winter were 7.5%,6.0%,11.3% and 9.9%,respectively.Conclusions The average infection rate of mycoplasma pneumoniae in Kunming is 8.8%.The infection rate of children at school age is much higher than that of infants.Mycoplasma pneumoniae infection is more common in autumn and winter.
    Comprehensive evaluation on quality of child health care in China based on TOPSIS method,RSR method and linear interpolation method
    BAO Xiao-bo,PAN Na,YANG Shu-xiang,LIU Yi-ning,LI Wang-chen,LI Xiang-yun
    2017, 25(9):  967-966.  DOI: 10.11852/zgetbjzz2017-25-09-32
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    Objective To evaluate the application value of three comprehensive methods in children's health care,and to understand the quality and development of children's health care work in 2014.Method TOPSIS method,RSR method and linear interpolation method were used for the comprehensive evaluation of child care work in 2014.Spearman correlation was conducted to analyze the consistence and difference of the ranked results among three kinds of comprehensive evaluation method by SPSS 17.0.Results There were differences among evaluation results of the three methods.In order to ensure the objectivity of the evaluation results,three methods were integrated and the results were displayed that the top three regions were Jiangsu,Shanghai and Shaanxi,and the sections listed the last three were Qinghai,Xinjiang and Tibet.Spearman correlation analysis,showed that the consistence between TOPSI method and linear interpolation method was the highest (r=0.969,P=0.000),followed by the correlation between TOPSIS method and RSR method (r=0.883,P=0.000),and the correlation between RSR method and linear interpolation method (r=0.795,P=0.000).Conclusions The ranked results by using TOPSIS method,RSR method,and linear interpolation method are highly correlated.The rank results will be more objectively,and will comprehensively reflect the situation of child health care in various provinces and cities by the conjunction of comprehensive evaluation with multiple methods.