Dynamic analysis of growth retardation and the severity of bronchopulmonary dysplasia
- XU Ru-zheng, SUN Bin
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Objective To dynamically monitor the increase of body weight, body length and head circumference of children from birth to discharge, and to analyze the correlation between growth retardation and severity of bronchopulmonary dysplasia(BPD)in different periods, so as to provide reference for clinical diagnosis and treatment of BPD. Method The data of body weight, body length, head circumference, gestational age and oxygen therapy were collected from 167 infants admitted to the NICU of Children's Hospital of Suchou University from January 1st, 2016 to December 31st, 2019 who were diagnosed with BPD within 24 hours after birth. Results A total of 159 children with BPD met the inclusion criteria, including 79 cases with mild BPD, 52 cases with moderate BPD, and 28 cases with severe BPD. There were significant differences on birth weight, male infants, antenatal corticosteroids, mechanical ventilation, oxygen therapy duration among children in different severity groups(χ2=13.958, 7.451, 11.287, 14.346, Z=14.750,P<0.05 or <0.01). There were significant difference on body weight, length and head circumference between children with or without growth retardation (Hweight=-5.429, Hlength=-9.632, Hhead circumference=-9.632, all P＜0.001). And the differences were significant between the two groups on the 28th days after birth (Hweight=-6.726, Hlength=-6.254, Hhead circumference=-6.254, all P<0.001) and at corrected gestational age of 36 weeks (Hweight=-7.091,Hlength=-7.178, Hhead circumference=-7.178, all P<0.001). Conclusions Growth retardation of body weight and length may be related to the severity of BPD. In clinical practice, preterm infants should be given reasonable nutrition in order to promote uniform growth.