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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2023, Vol. 28 ›› Issue (8): 948-953.doi: 10.12092/j.issn.1009-2501.2023.08.011

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Analysis of 197 cases of pentoxifylline injection and exploring supervision mode of rational drug use in hospitals

CHEN Qun1, ZHU Heping1, YUAN Xiaolong2   

  1. 1Department of pharmacy, Wuhu Hospital of Traditional Chinese Medicine, Wuhu 241000, Anhui, China; 2Department of Pharmacy, the Second Affiliated Hospital of Wannan Medical College, Wuhu 241000, Anhui, China
  • Received:2023-04-23 Revised:2023-06-12 Online:2023-08-26 Published:2023-08-29
  • About author:陈群,女,硕士,主管药师,主要从事临床药学研究。 E-mail:395663924@qq.com

Abstract:

AIM: To analyze and evaluate the use of pentoxifylline injection in a hospital, and explore effective supervision mode, so as to provide some reference for clinical rational drug use. METHODS: A total of 197 inpatients with pentoxifylline injection who were discharged from October 2021 to June 2022 were randomly selected from HIS system. Referring to drug-label and collecting evidence-based medical evidence to judge the rationality of use of pentoxifylline injection in the hospital. RESULTS: Among the 197 medical records extracted, 140 medical records were unreasonable, accounting for 71.07% of the total medical records. Among them, 111 cases (79.29%) were no indication for use, 13 cases (9.29%) were off-label, 2 cases (1.43%) were inappropriate for indications, 13 cases (9.29%) were inappropriate for usage and dosage, and 1 case (0.71%) was inappropriate for solvent. CONCLUSION: The irrational use of pentoxifylline injection in this hospital is serious. It is necessary to standardize its clinical application through the intervention of smart pharmacy management mode, improving system, strengthening medication education and other ways. 

Key words: pentoxifylline injection, rational drug use, medical order evaluation, supervision mode

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