关键词: 婴幼儿哮喘, 支气管哮喘, 遗传度, Logistic回归分析

Abstract: Objective To explore the mode of inheritance and genetic correlation was observed between the two of infant asthma and bronchial asthma, and provide a theoretical basis for the three grade prevention of asthma. Method Through the Falconer regression method to estimate the heritability of infant asthma and bronchial asthma, Logistic regression analysis of the major risk factors was summarized, S-N-K method were compared. Results The heritability for infants with asthma was (80.53±7.85)%, the heritability of bronchial asthma was (78.87±6.99)%.There was no significant difference between the two risk factors. Conclusion Genetic factors play a major role in the onset and development of asthma, other risk factors play a role, both have close correlation.Therefore, prevention of asthma in infants and young children can effectively reduce and prevent the occurrence of asthma.

Key words: infant asthma, bronchial asthma, heritability, Logistic regression analysis