关键词: 新生儿, 25-羟维生素D₃, 维生素D缺乏

Abstract: 【Objective】 To observe the changes of serum 25-(OH)D₃ in newborns in different gestation ages,to know nutritional status of the vitamin D,and study exogenous vitamin D supplements. 【Methods】 Ninety-five newborns were studied.All the newborns were divided into three groups according to gestational age:Group A had 30 newborns(GA≤33 weeks),Group B had 34 newborns(33 weeks<GA<37 weeks),Group C had 31 newborns(37 weeks≤GA<42 weeks).Serum 25-(OH)D₃ was measured within 1 d,14 d,30 d after birth. 【Results】 The mean serum 25-(OH)D₃ concentration[(35.03±9.72) nmol/ L] of A group were lower than the mean serum 25-(OH)D₃ concentration of B and C group[(41.31±11.35) nmol/L,(42.05±15.93) nmol/L] (P<0.05)1 d after birth.76.8%,53.7% and 75.8% of newborns had vitamin D deficiency (serum 25-(OH)D₃ levels ＜50 nmol/L)in 1 d,14 d and 30 d after birth. 【Conclusion】 The vitamin D deficiency of newborns is common,and the vitamin D should be supplied as early as after birth.

Key words: newborn, 25-(OH)D₃, vitamin D deficiency