不同剂量托烷司琼预防术后镇痛恶心呕吐的效果

中国临床药理学与治疗学 ›› 2011, Vol. 16 ›› Issue (9): 1057-1058.

不同剂量托烷司琼预防术后镇痛恶心呕吐的效果

章杭, 张帆, 李丰

杭州市第一人民医院吴山院区麻醉科,杭州 310002,浙江

收稿日期:2011-07-19 修回日期:2011-08-30 出版日期:2011-09-26 发布日期:2020-09-16
作者简介:章杭,男,主治医师,研究方向:临床麻醉学。Tel: 13018934608 E-mail: 416743950@qq.com

Effect of different doses of tropisetron in postoperative nausea and vomiting

ZHANG Hang, ZHANG Fan, LI Feng

Department of Anesthesiology, Wushan District, Hangzhou First People's Hospital, Hangzhou 310002, Zhejiang, China

Received:2011-07-19 Revised:2011-08-30 Online:2011-09-26 Published:2020-09-16

摘要/Abstract

摘要： 目的: 探讨不同剂量的托烷司琼预防术后镇痛恶心呕吐的效果。方法: 将本院2005年1月至2010年12月收治的择期进行胸部手术的150例患者,随机分为A、B、C三组,每组50例。A组在镇痛泵加入 5 mg 托烷司琼,B组加入 10 mg 托烷司琼,C组采用 0.9%生理盐水,比较三组患者的疗效、药物的不良反应。结果: A、B两组在防止术后恶心呕吐的疗效方面无统计学差异,但均显著优于C组(P<0.05)。A、B两组的不良反应显著多于C组(P<0.05),但均可以耐受。结论: 5 mg、10 mg 托烷司琼预防术后镇痛恶心呕吐的效果均较为满意,且不良反应可以耐受。

关键词: 术后恶心呕吐, 托烷司琼

Abstract: AIM: To study the analgesic effect of different doses of tropisetron in preventing postoperative nausea and vomiting. METHODS: ASA grade Ⅰ-Ⅱ score of 150 cases, which was admitted for elective thoracic surgery in our hospital from January 2005 to December 2010, were divided into A, B, C three groups, n=50, A group using the analgesia adding 5 mg tropisetron, B group using the analgesia with 10 mg tropisetron, C group using 0.9% saline, compared the postoperative nausea and vomiting efficacy and adverse drug reactions of three groups of patients. RESULTS: A, B groups had no significant efficacy differences in the prevention of postoperative nausea and vomiting, but were significantly better than C group, P<0.05. The adverse reactions of A, B groups were significantly more than C Group, P<0.05, but can be tolerated.P<0.05. A, B groups of adverse reactions was significantly more than Group C, P<0.05, but can be tolerated. CONCLUSION: The analgesic effects in preventing postoperative nausea and vomiting of 5 mg, 10 mg tropisetron are more satisfied, and adverse reactions can be tolerated.

Key words: Postoperative nausea and vomiting, Tropisetron

中图分类号:

R614.1

章杭, 张帆, 李丰. 不同剂量托烷司琼预防术后镇痛恶心呕吐的效果[J]. 中国临床药理学与治疗学, 2011, 16(9): 1057-1058.

ZHANG Hang, ZHANG Fan, LI Feng. Effect of different doses of tropisetron in postoperative nausea and vomiting[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(9): 1057-1058.

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