关键词: 补肾延寿胶囊, 碳粒廓清, 淋巴细胞转化, 溶血素迟发型超敏反应

Abstract: Aim The effect of capsule bushenyanshou (BSYS),a compound of traditional Chinese medicine,on the immunopharmacological activities of mice was investigated. Methods The indexes of immunopharmacological activity, such as the clearance rate of charcoal particles, the lymphocyte transformation and the content of serum hemolysin, were measured.Results Capsule BSYS (400, 800 mg·kg^-1,qdX12) markedly increased the clearance rate of iv charcoal particles and the lymphocyte transformation stimulated in vivo by PHA in mice. In hydrocortisone-treated mice(15 mg·kg^-1, scqdX 5),capsule.BSYS significantly enhanced the content of serum hemolysin and the weights of spleen and thymus. The results also demonstrated capsule BSYS performed a sighted inhibition of the delayed type hypersensitivity in mice.Conclusion Capsule BSYS has the capacity of immunological intensification and regulation.

Key words: capsule bushenyanshou, lymphocyte transformation, charcoal particles clearance, serum hemolysin, hydrocortisone treatment, hypersensitivity