经皮冠状动脉介入治疗术中无复流现象防治研究进展

摘要/Abstract

摘要： 随着经皮冠状动脉介入治疗方法在临床上得到广泛应用,急性ST段抬高性心肌梗死直接经皮冠状动脉介入治疗(PCI)的比例越来越高。但急诊PCI过程中,常常发生无复流现象,严重影响患者的预后。本文就无复流的可能机制和处理作一简要介绍。

关键词: 经皮冠状动脉介入, 无复流, 慢血流, 血管扩张剂, 血小板糖蛋白受体拮抗剂, 血栓抽吸, 远端保护装置

Abstract: As percutaneous coronary intervention is widely used in clinic, more and more acute ST-segment elevation myocardial infarction patients undergo direct PCI. However, no-reflow phenomenon seriously affects the prognosis of patients during emergent PCI. The possible mechanisms and therapies of no-reflow phenomenon will be introduced briefly in this review.

Key words: Percutaneous coronary intervention, No-reflow, Slow reflow, Vasodilator agents, Platelet glycoprotein receptor antagonist, Thrombus aspiration, Distal protection equipment

中图分类号:

R541.4

李晓倩, 柯永胜. 经皮冠状动脉介入治疗术中无复流现象防治研究进展[J]. 中国临床药理学与治疗学, 2011, 16(5): 595-600.

LI Xiao-qian, KE Yong-sheng. Progression of no-reflow prevention and treatment in percutaneous coronary intervention[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(5): 595-600.

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