关键词: 百日咳, 流行特征, 发病率

Abstract: Objective To understand the epidemiological characteristics and epidemic trend of pertussis in Hubei province in 2005-2015,and provide scientific basis for the strategy of monitoring and controlling pertussis. Method The individual data of pertussis cases from National Notifiable Disease Reporting System in Hubei during January 1^st 2005 to December 31^st 2015 were analyzed descriptively. Results Totally 565 cases were reported in Hubei in 2005-2015,with no cases died.The reported incidence of pertussis declined from 0.163 to 0.047 cases per 100 000 in 2005-2009,keep a low level from 0.028 to 0.056 cases per 100 000 in 2010-2013,showed a noticeable rising trend in 2014,and reached 0.217 cases per 100 000 in 2015.The disease occurred all through the year and peaked in March to September,which accounted for 83.4% of the total cases that mainly occurring in infants,around 62.7% cases were less than 1 year old.A proportion of 85.5% of the cases were scattered children. Conclusions Laboratory diagnosis Methods of pertussis should be improved.The proportion of pertussis cases diagnosed by laboratory should be increased,and the incidence should be estimated by active surveillance to effectively control and prevent prevalence of pertussis with reinforce of full-course immunization.

Key words: pertussis, epidemiological characteristic, incidence