关键词: 幽门螺旋杆菌, 危险因素, 婴幼儿, 口腔

Abstract: Objective To identify the risk factors of helicobacter pylori (Hp) infection in infants and young children in Suzhou City. Methods A random sample of 441 infants and young children who had regular physical examinations in Child Healthcare Department of Suzhou Municipal Hospital were enrolled as research subjects.Oral Hp infection was diagnosed by method of saliva test board (HPS).Related demographic data were obtained by a structured questionnaire sent to the parents of these children.Categorical variables were analysed with chi-square test in univariate factor analysis.The substantially significant factors were included in Logistic regression analysis. Results Among 441 infants and young children,212(48.1%) were diagnosed as HPS test positive.HPS positive rates in the age periods of 0 months～,6 months～,1 years old～,2～3 years old were 27.6%,56.1%,56.7%,and 63.5% respectively,which meaned obviously that the prevalence increased with age.The following factors were the high risks of Hp infection:complementary foods introduction,age,too much family members,children personal hygiene practices such as chewing fingers,caregivers' children-raising patterns such as chewing and crushing food before feeding and caretaker personal habits (no washing hands before eating) and families' stomach diseases history. Conclusions The main transmission routes of Hp infection are oral to oral and fecal to oral.It makes great sense to use individual plates or serving chopsticks in family,pay attention to hands hygiene (including washing hands before breast feeding and preparing food),educate infants to develop excellent dietary health habits,and improve family living standards.

Key words: helicobacter pylori, risk factor, infants and young children, oral