关键词: 杜氏肌营养不良, 生物电阻抗分析, 体脂百分比

Abstract: Objective To analyze the body composition of children with duchenne muscular dystrophy (DMD) by bioelectrical impedance analysis (BIA), and to compare the consistency of body mass index (BMI) with the percentage of body fat (PBF) when assessing the overweight of DMD children. Methods A total of 39 male DMD children were enrolled in case group from August 2015 to February 2017 in Neuromuscular Department of the Third Hospital of Hebei Medical University, and 46 healthy boys were randomly selected as control group during the same period.BIA was used to test body composition in two groups. Results There was no significant difference on fat content and BMI between the two groups (P＞0.05).The height, weight, body water, protein, inorganic salt, muscle mass and basal metabolic rate (BMR) of DMD children were significantly lower than those in control group (P<0.05).However, the PBF of DMD children was higher than that of the control group (P<0.05).There was positive correlation between PBF and age in DMD children (r=0.546, P<0.05).BMI was poorly consistent with PBF in determining the overweight of children with DMD (Kappa=0.352, P<0.05). Conclusions Compared with healthy children with the same age and gender, the nutritional status of DMD children is poor.BIA can more accurately assess the nutritional status of patients than using BMI.

Key words: duchenne muscular dystrophy, bioelectrical impedance analysis, percentage of body fat