关键词: 缺氧缺血性脑损伤, 新生儿, 文献计量

Abstract: Objective To explore the research hotspots and development trends of neonatal hypoxic-ischemic brain damage (HIBD) at home and abroad, so as to provide reference and guidance for further research in the later stage. Methods Literature published till February 31st 2019 was searched from PubMed, Web of Science, FMRS, CNKI, WanFang and WeiPu database, and the basic methods of bibliometrics were used.Data were analyzed from the number of countries, subject distribution, journals and authors, institutions and funds, high frequency key words.A co-word matrix for high-frequency keywords was established and then cluster analysis was performed. Results 1)A total of 5 594 articles published in 1 246 journals were selected, including 205 journals with influential factors over 5. 2) The top three countries in terms of article volume on neonatal HIBD were the United States, China and Japan.3) The United States has formed a core group of authors in the field of neonatal HIBD, with high-quality journals, playing an irreplaceable role in this field.However, the core force of research on neonatal HIBD has not been formed in China.4) Eight of the top 10 research institutions in China were from advanced institutions, and the most research institutions were from Zhengzhou University, while the more in-depth researches were in Shanghai. Conclusions At present, China plays a leading role in the researches on neonatal HIBD.Multi-disciplinary, multi-level and multiregional large samples researches in this field are warranted in order to better promote clinical research.It is an urgent task to develop new drugs and targets for neonatal hypoxic-ischemic therapy, and the exploration of the role of autophagy in HIBD and related mechanisms may provide new ideas.

Key words: hypoxic-ischemic brain damage, neonates, bibliometric