关键词: 儿童孤独症, 幼儿ASD筛查量表, 智力发育, 联合筛查, 预测准确性

Abstract: Objective To evaluate the application of screening tools for autism spectrum disorder (ASD) in children in the primary child healthcare service,so as to provide advisable information for selecting appropriate tools. Methods A total of 2 639 children received physical examination in Minhang Maternal and Child Health Care Center from 2013 to 2018 were selected in this study,of whom 2 525 were conducted CHAT-23 screening test and 1 979 received Developmental Screening Test for Child under six(DST).Both screening tests above and autism diagnosed results were collected from Minhang electronic health record retrospectively,so as to compare the predictive value of single screening test alone with joint screening test. Results Finally 34 children were diagnosed with ASD among 2 639 children.And the sensitivity CHAT-23 for screening ASD was 0.265.Compared with CHAT-23 screening ASD alone,CHAT-23 combined with DST suspicious results of DST together could higher the sensitivity (0.906 vs.0.265) and Youden index (0.481 vs.0.261),which is of great significance for avoid missed diagnosis. Conclusion Considering the high accuracy of both CHAT-23 results filled out by parents and DST results conducted by physicians,this method will improve the of screening child autism and help early detection,diagnosis and intervention of child autism,and is worthy being used in primary child health care service.

Key words: child autism, CHAT-23 Screening Scale, intelligence development, joint screening, accuracy of prediction