[1] Budden KF,Gellatly SL,Wood DL,et al.Emerging pathogenic links between microbiota and the gut-lung axis[J].Nat Rev Microbiol,2017,15(1):55-63. [2] Kumar R,Sood U,Gupta V,et al.Recent advancements in the development of modern probiotics for restoring human gut microbiome dysbiosis[J].Indian Microbiol,2020,60(1):12-25. [3] 冯梦妮,柯华,李占魁,等.益生菌预防早产儿坏死性小肠结肠炎的研究进展[J].中国儿童保健杂志,2019,27(6):629-632. [4] Whelan FJ,Waddell B,Syed SA,et al.Culture-enrichedmetagenomic sequencing enables in-depth profiling of the cystic fibrosis lung microbiota[J].Nat Microbiol,2020,5(2):379-390. [5] Pammi M,Lal CV,Wagner BD,et al.Airway microbiome and development of bronchopulmonary dysplasia in preterm infants:a systematic review[J].Pediatr,2019,204:126-133.e2. [6] Dominguez-Bello MG,Costello EK,Contreras M,et al.Delivery mode shapes the acquisition and structure of the initialmicrobiota across multiple body habitats in newborns[J].Proc Natl Acad Sci U S A,2010,107(26):11971-11975. [7] Lal CV,Kandasamy J,Dolma K,et al.Early airway microbial metagenomic and metabolomic signatures are associated with development of severe bronchopulmonary dysplasia[J].Am J Physiol Lung Cell Mol Physiol,2018,315(5):L810-L815. [8] Martinez KA 2nd,Romano-Keeler J,Zackular JP,et al.Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice[J].PLoS ONE,2018,13(5):e0197439. [9] Satokari R,Grönroos T,Laitinen K,et al.Bifidobacterium and Lactobacillus DNA in the human placenta[J].Lett Appl Microbiol,2009,48(1):8-12. [10] AlAlam D,Danopoulos S,Grubbs B,et al.Human fetal lungs harbor a microbiome signature[J]Am J Respir Crit Care Med,2020,201(8):1002-1006. [11] Bushman FD.De-discovery of the placenta microbiome[J].Am J Obstet Gynecol,2019,220(3):213-214. [12] Lohmann P,Luna RA,Hollister EB,et al.The airway microbiome of intubated premature infants:characteristics and changes that predict the development of bronchopulmonary dysplasia[J].Pediatr Res,2014,76(3):294-301. [13] Beck TF,Campeau PM,Jhangiani SN,et al.FBN1 contributing to familial congenital diaphragmatic hernia[J].Am J Med Genet A,2015,167A(4):831-836. [14] Ryan FJ,Drew DP,Douglas C,et al.Changes in the composition of the gut microbiota and the blood transcriptome in preterm infants at less than 29 weeks gestation diagnosed with bronchopulmonary dysplasia[J].mSystems,2019,4(5):pii:e00484-19. [15] Resch B,Gutmann C,Reiterer F,et al.Neonatal ureaplasma urealyticum colonization increases pulmonary and cerebral morbidity despite treatment with macrolide antibiotics[J].Infection,2016,44(3):323-327. [16] Gill N,Wlodarska M,Finlay BB.The future of mucosal immunology:studying an integrated system-wide organ[J].Nat Immunol,2010,11(7):558-560. [17] Debock I,Flamand V.Unbalanced neonatal CD4(+) T-cell immunity[J].Front Immunol,2014,5:393. [18] Rawls JF,Mahowald MA,Ley RE,et al.Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection[J].Cell,2006,127(2):423-433. [19] Tirone C,Pezza L,Paladini A,et al.Gut and lung microbiota in preterm infants:immunological modulation and implication in neonatal outcomes[J].Front Immunol,2019,10:2910. [20] Anand S,Mande SS.Diet,microbiota and gut-lung connection[J].Front Microbiol,2018,9:2147. [21] Morrison DJ,Preston T.Formation of short chain fatty acids by the gutmicrobiota and their impact on human metabolism[J].Gut Microbes,2016,7(3):189-200. [22] Gollwitzer ES,Saglani S,Trompette A,et al.Lung microbiota promotes tolerance to allergens in neonates via PD-L1[J].Nat Med,2014,20(6):642-647. [23] Collins JJP,Tibboel D,de Kleer IM,et al.The future of bronchopulmonary dysplasia:emerging pathophysiological concepts and potential new avenues of treatment[J].Front Med (Lausanne),2017,4:61. [24] Willis KA,Siefker DT,Aziz MM,et al.Perinatal maternal antibiotic exposure augments lung injury in offspring in experimental bronchopulmonary dysplasia[J].Am Physiol Lung Cell Mol Physiol,2020,318(2):L407-L418. [25] Tanaka S,Tsumura K,Nakura Y,et al.New antibiotic regimen for preterm premature rupture of membrane reduces the incidence of bronchopulmonary dysplasia[J].Obstet Gynaecol Res,2019,45(5):967-973. [26] Cantey JB,Huffman LW,Subramanian A,et al.Antibiotic exposure and risk for death or bronchopulmonary dysplasia in very low birth weight infants[J].Pediatr,2017,181:289-293. [27] Alonso-Ojembarrena A,Martínez-Díaz JV,Lechuga-Sancho AM,et al.Broad spectrum antibiotics in newborns increase multi-drug resistant infections[J].Chemother,2019,31(2):81-85. [28] Fajardo C,Alshaikh B,Harabor A.Prolonged use of antibiotics after birth is associated with increased morbidity in preterm infants with negative cultures[J].Matern Fetal Neonatal Med,2019,32(24):4060-4066. |