癫痫儿童相关细胞因子变化及意义

中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (10): 924-926.

癫痫儿童相关细胞因子变化及意义

李红综述, 马海燕审校

青岛大学医学院附属青岛市市立医院东院区,山东青岛 266071

收稿日期:2011-04-02 发布日期:2011-10-06 出版日期:2011-10-06
通讯作者: 马海燕,E-mail:mahy_cn@sohu.com
作者简介:李红(1963-),女,山东人,副主任医师,本科学历,主要研究方向为小儿神经系统疾病
基金资助:
青岛市公共领域科技支撑计划资助项目(08-2-1-2-nsh)

Received:2011-04-02 Online:2011-10-06 Published:2011-10-06

摘要/Abstract

摘要： 细胞因子是由多种细胞产生的具有广泛生物学活性的小分子蛋白质。癫痫作为一种免疫相关性神经系统疾病,其发生发展与细胞因子有着密切关联,诸多细胞因子与其受体结合后可改变中枢神经系统兴奋性,参与癫痫发病过程。笔者将对白细胞介素-2(IL-2) 、白细胞介素-6(IL-6) 、肿瘤坏死因子-α(TNF-α)等具有广泛生物学作用的细胞因子与癫痫的发病机制作一综述,进一步揭示细胞因子在癫痫发病中的作用。

关键词: 癫痫, 细胞因子, 白介素, 肿瘤坏死因子

中图分类号:

R749.94

李红综述, 马海燕审校. 癫痫儿童相关细胞因子变化及意义[J]. 中国儿童保健杂志, 2011, 19(10): 924-926.

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