促红细胞生成素在新生儿缺氧缺血性脑病中的研究进展

中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (8): 729-731.

促红细胞生成素在新生儿缺氧缺血性脑病中的研究进展

王钰综述, 尹晓娟审校

北京军区附属八一儿童医院,北京 100700

收稿日期:2011-04-27 发布日期:2011-08-06 出版日期:2011-08-06
通讯作者: 尹晓娟,E-mail:yyinxiaojuan@163.com
作者简介:王钰(1986-),女,山东人,在读硕士研究生,主要从事新生儿脑修复的临床与基础研究

Received:2011-04-27 Online:2011-08-06 Published:2011-08-06

摘要/Abstract

摘要： 缺氧缺血性脑病(hypoxic-ischemic encephalopathy, HIE)是因为围生期窒息缺氧所引起的缺氧性缺血脑损害,是新生儿时期危害性最大的疾病之一,重度HIE患儿可造成死亡,部分存活儿可留有癫痫、脑瘫、学习困难等神经系统后遗症,目前尚缺乏有效的治疗方法。促红细胞生成素(erythropoietin, Epo)对HIE可能具有潜在的脑保护作用,本文就Epo可能的脑保护作用、脑保护的机制以及Epo应用中的副作用进行综述,以其提高人们对Epo在HIE脑保护作用中的认识。

中图分类号:

R722.1

王钰综述, 尹晓娟审校. 促红细胞生成素在新生儿缺氧缺血性脑病中的研究进展[J]. 中国儿童保健杂志, 2011, 19(8): 729-731.

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