中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (8): 743-745.

• 临床研究与分析 • 上一篇    下一篇

顺义区3~7岁学龄前儿童血铅水平与行为问题关系的研究

刘雅静1,贾美香2,何亚萍1,王秀云1,项征1,崔文红1,李雪玲1,刘建华1,冀伟龙1   

  1. 1 北京市顺义区妇幼保健院,北京 101300;
    2 北京大学精神卫生研究所,北京 100083
  • 收稿日期:2011-03-21 发布日期:2011-08-06 出版日期:2011-08-06
  • 作者简介:刘雅静(1980-),男,北京人,主治医师,硕士学位,主要研究方向为儿童保健和儿童心理行为
  • 基金资助:
    首都医学发展科研基金(2007-3181)

Study on the relationship between the blood lead level and behavior problems in the preschool children aged 3~7 years old in Shunyi district

LIU Ya-jing1, JIA Mei-xiang2, HE Ya-ping1, WANG Xiu-yun1, XIANG Zheng1, CUI Wen-hong1, LI Xue-ling1, LIU Jian-hua1, JI Wei-long1   

  1. 1 Maternal and Child Health Care Hospital of Shunyi District, Beijing 101300, China;
    2 Peking University Institution of Mental Health, Beijing 100083, China
  • Received:2011-03-21 Online:2011-08-06 Published:2011-08-06

摘要: 【目的】 了解北京市顺义区3~7岁学龄前儿童血铅水平,分析其分布规律,初探铅暴露对3~7岁学龄前儿童行为问题产生的影响。 【方法】 采用整群随机抽样的方法于2009年4-6月对顺义区5所幼儿园1 307名3~7岁在园儿童采集手指末梢血测定血铅水平,同时采用Achenbach量表(Child Behavior Checklist, CBCL)进行行为问题评估。按照检测的血铅值将研究对象分为高血铅组(≥100 μg/L)和低血铅组(<100 μg/L)。男童CBCL总粗分≥42分,女童≥45分即判定为有行为问题。 【结果】 北京市顺义区3~7岁学龄前儿童血铅对数均值为3.328±2.765,血铅值≥100 μg/L占总测查人数的1.22%,血铅值≥200 μg/L占0.15%。高血铅组行为问题检出率为76.47%,低血铅组CBCL行为问题检出率为10.85%。高血铅组CBCL粗分及行为问题检出率均显著高于低血铅组,差异有高度统计学意义(P<0.001)。男童高血铅组在攻击因子、多动因子、违纪因子检出率显著高于低血铅组(P<0.05),女童高血铅组违纪因子检出率显著高于低血铅组(P<0.001)。 【结论】 高血铅的学龄前儿童行为问题较血铅值<100 μg/L儿童多,今后应加大宣传力度,降低铅中毒对学龄前儿童的危害。

关键词: 高血铅, 学龄前儿童健康, 行为问题

Abstract: 【Objective】 To observe blood lead level and distributed characteristics among children of 3~7 years old in Shunyi district in Beijing and to explore the effects of lead poisoning on preschool children behaviors. 【Methods】 1 307 children of 3~7 years old were investigated from April to June 2009. All subjects were selected from 5 kindergartens through a clustered-random sampling in Shunyi district.Blood lead level was measured and behavior problems were made by CBCL.All children were divided into 2 group(high blood lead group and low blood lead group)by blood lead beyond or below 100 μg/L .The behavior problems were identified while the total crude scores of CBCL beyond 42 in boys and 45 in girls. 【Results】 The geometric mean of blood lead was (3.328±2.765) with 1.22% of those ≥100 μg/L,and 0.15%≥200 μg/L.The median of CBCL total crude scores in high blood lead group was significantly higher than those of low blood lead group(P<0.001).The ratio of behavior problems in high blood lead group(76.47%) was significantly higher than that of low blood lead group(10.85%)(P<0.001).The ratios of behavior of attack, hyperactivity and disobey were significantly higher in high blood lead group than those of low blood lead group in boys(P<0.05). The ratio of behavior of disobey was significantly higher in high blood lead group than that of low blood lead group in girls(P<0.001). 【Conclusions】 Preschool children lead poisoning is associated with their behavior problems. Promoting healthy information can alleviate danger of high blood lead.

Key words: high blood lead, preschool children&apos, s health, behavior problems

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