中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (3): 280-281.

• 经验交流 • 上一篇    下一篇

学龄前儿童血清胱抑素C正常参考范围的调查

赵丽华,何谦,王香玲,安哲,张磊   

  1. 西安交通大学医学院第二附属医院检验科,陕西 西安 710004
  • 收稿日期:2011-08-09 发布日期:2012-03-06 出版日期:2012-03-06
  • 作者简介:赵丽华(1960-),女,河南人,副主任技师,本科学历,主要从事临床检验学研究

Investigation of the reference values of serum cystatin C within healthy preschool children

ZHAO Li-hua,HE Qian,WANG Xiang-ling,AN Zhe,ZHANG Lei   

  1. Department of Clinical Laboratories,the Second Affiliated Hospital of Medical Collage,Xi'an Jiaotong University,Xi'an,Shaanxi 710004,China
  • Received:2011-08-09 Online:2012-03-06 Published:2012-03-06

摘要: 【目的】 通过检测学龄前儿童的血清胱抑素C, 旨在建立不同时期学龄前儿童的正常参考值范围, 为临床医生提供有意义的数据参考。 【方法】 应用全自动生化分析仪检测学龄前儿童474例和正常成人172例空腹血清胱抑素C。 【结果】 婴儿组、幼儿组、学龄前组及正常成人组Cys C正常值范围分别为0.62~1.74、0.47~1.15、0.41~0.97 mg/L和0.46~1.02 mg/L;各组与正常成人组比较发现, 婴儿组、幼儿组与正常成人组参考值差异有统计学意义(P<0.05),学龄前组与正常成人组参考值差异无统计学意义(P>0.05);将各组按性别分别比较,各组内男女间Cys C参考值差异均无统计学意义(P>0.05);以正常成人组参考值范围为对照,婴儿组、幼儿组超限检出率分别为56.8%、11.1%。 【结论】 婴儿组、幼儿组儿童可与成人采用不同的Cys C参考值范围,学龄前组可与成人采用相同的Cys C参考值范围,且参考值范围与性别无关。

关键词: 胱抑素C, 学龄前儿童, 正常参考范围

Abstract: 【Objective】 To investigate the reference values of serum cystatin C within the healthy preschool children. 【Method】 The automatic biochemical analyzer(OLYMPUS AU2700)was used to detect the level of serum cystatin C of 474 healthy preschool children and 172 normal adults.Then the data were analyzed with statistical methods. 【Results】 The value of cystatin C of infant group, child care group,preschool group and normal adult group were 0.62~1.74,0.47~1.15,0.41~0.97 mg/L and 0.46~1.02 mg/L,respectively.Infant group,child care group and normal adult group reference values were significantly different (P<0.05).There was no difference between preschool group and normal adult group.Each of the groups were compared by sex,between boys and girls within each group of Cys C reference values were not significantly different (P>0.05).Normal adult reference range for the control group,infant group,child care group overrun detection rates were 56.8%,11.1%. 【Conclusions】 Infant group, child care group and adult group can adopt different reference values of serum cystatin C,preschool group and normal adult group can use the same.There is no difference between boys and girls for serum cystatin C.

Key words: cystatin C, pre-school children, reference value

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