孕妇血清唾液酸与正常新生儿的体格生长

中国儿童保健杂志 ›› 2013, Vol. 21 ›› Issue (8): 789-792.

孕妇血清唾液酸与正常新生儿的体格生长

乔阳^1,2 ,白增华²,王熲²,金华¹,柏丹丹¹,马亚萍¹,古桂雄¹

1 苏州大学儿科研究所,浙江江苏 215003;
2 山西省妇幼保健院,山西太原 030013

收稿日期:2013-06-18 发布日期:2013-08-06 出版日期:2013-08-06
通讯作者: 古桂雄,E-mail:szggx000@163.com
作者简介:乔阳(1970-) 女,山西人,副主任医师,博士学位,主要从事儿童生长发育研究。
基金资助:
江苏省普通高校研究生科研创新计划项目(CXLX11_0085);苏州市科技发展计划(SYS201145)

Effects of serum sialic acid in pregnant women on neonatal physical growth

QIAO Yang^1,2,BAI Zeng-hua²,WANG Jiong²,JIN Hua¹,BAI Dan-dan¹,MA Ya-ping¹,GU Gui-xiong¹

1 Pediatric Research Institute of Soochow University,Suzhou,Zhejiang 215003,China;
2 Shanxi Maternal and Child Health Hospital,Taiyuan,Shanxi 030013,China

Received:2013-06-18 Online:2013-08-06 Published:2013-08-06
Contact: GU Gui-xiong,E-mail:szggx000@163.com

摘要/Abstract

摘要： 目的研究孕妇不同妊娠期的血清唾液酸含量、脐血清唾液酸含量、唾液酸胎盘转运率与新生儿体格生长的关系。方法采取前瞻性队列研究的方法,从妊早、中、晚期至分娩时,分析孕期血清唾液酸水平与子代出生体重、身长、头围和Kaup指数的关系。结果妊早、中、晚期孕妇不同血清唾液酸含量的新生儿出生体重、出生身长、出生头围及Kaup指数差异均无统计学意义(P>0.05);不同脐血清唾液酸和唾液酸胎盘转运率的新生儿出生体格差异亦无统计学意义(P>0.05)。结论妊娠期的唾液酸含量、新生儿脐唾液酸含量和唾液酸胎盘运转率对新生儿出生体格生长无显著影响,唾液酸不会对婴儿造成肥胖的影响,唾液酸胎盘转运率只是反映唾液酸通过胎盘的一个度量,可以衡量胎儿当时生长发育的营养需求。

关键词: 血清, 唾液酸, 体格生长, 新生儿

Abstract: Objective To investigate the correlation between the maternal serum sialic acid (SA) contents,umbilical cord serum SA contents,SA placenta transport rate with infant early growth and development. Methods Prospective cohort study was carried from early pregnancy,followed up to middle,late pregnancy and delivery.The relationships between maternal serum sialic acid at three stages of pregnancy,with offspring birth weight,height,head circumference and Kaup index were carried out. Results There were no significant differences in the neonatal birth weight,birth length,birth head circumference and Kaup index respectively in different serum SA contents in early pregnancy,middle pregnancy and late pregnancy(P>0.05).And there were no significant differences of umbilical cord serum SA and SA placenta transfer rate on neonatal outcome either(P>0.05). Conclusions There are no significant effects of maternal serum SA contents during pregnancy,fetal umbilical cord SA levels and SA placenta transfer rate on birth physical growth.SA doesn't cause obesity to infants.SA placenta transport rate can reflect the nutritional needs for fetal growth and development.

Key words: serum, sialic acid, physical growth, neonatal

中图分类号:

R179

乔阳 ,白增华,王熲,金华,柏丹丹,马亚萍,古桂雄. 孕妇血清唾液酸与正常新生儿的体格生长[J]. 中国儿童保健杂志, 2013, 21(8): 789-792.

QIAO Yang,BAI Zeng-hua,WANG Jiong,JIN Hua,BAI Dan-dan,MA Ya-ping,GU Gui-xiong. Effects of serum sialic acid in pregnant women on neonatal physical growth[J]. journal1, 2013, 21(8): 789-792.

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