脑性瘫痪相关易感基因多态性研究现状

doi:10.11852/zgetbjzz2015-23-04-12

摘要/Abstract

摘要： 随着围生医学的迅速发展,足月儿脑性瘫痪的发生率并未下降,这使得人们对脑性瘫痪病因学的研究范围逐渐从以前的围生期扩大到分娩前,进而关注到遗传因素。目前认为先天性感染、遗传、早产、损伤等,都是脑性瘫痪的主要病因,脑性瘫痪是基因与环境相互作用的结果。当前对脑性瘫痪相关易感基因多态性的研究多集中在遗传性血栓形成、载脂蛋白E和细胞因子的基因多态性,对其他影响相对较小的基因也做了多态性研究分析,但结果并未完全一致。本文就国内外在脑性瘫痪相关易感基因多态性研究上的现状做出综述供临床参考。

中图分类号:

R725.9

杜翔,梁松,吴兆芳,陈嘉,姜琨. 脑性瘫痪相关易感基因多态性研究现状[J]. 中国儿童保健杂志, 2015, 23(4): 374-376.

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