关键词: 参考区间, 维生素B1, 维生素B2, 血清, 广州, 儿童

Abstract: Objective To establish the normal reference range for serum vitamin B1 and B2 of healthy children in Guangzhou and to porovide evidence for clinical accurate judgment of vitamin B1 and B2 status in children. Methods Serum vitamin B1 and B2 of 1 442 healthy children (809 males,633 females)living in Guangzhou were examined by LK3000V Vitamin Analyzer.Then the data were analyzed with statistical methods. Results 1)There was no statistical difference between boys and girls for levels of serum vitamin B1 and B2 between every group defined by age within ten years old(P>0.05).2)The levels of serum vitamin B1[median(P2.5,P97.5)] defined by age were as follows:41.9(45.6,88.1)nmmol/L for 0~3 year-old group,65.5(45.6,98.4)nmol/L for 3~5 year-old group,72.9(46.3,105.8) for 5~17 year-old group and 80.6(46.7,115.9) for the adult group.The levels of serum vitamin B2 were as follows:285.6(197.3, 376.2)μg/L for 0~5 year-old group,297.9(208,387.4)μg/L for 5~17 year-old group and 308.2(280.6,394.7) μg/L for the adult group.3)Positive correlation was found between age and the level of serum vitamin B1 as well as that of serum vitamin B2. Conclusion Reference range for serum vitamin B1 for healthy children in Guangzhou is same among different age groups,while that for serum vitamin B2 need to be set up according two age groups by a five years old.

Key words: reference range, vitamin B1, vitamin B2, serum, Guangzhou, children