关键词: 行为问题, 双酚A, 性激素, 儿童

Abstract: Objective To investigate the prevalence and characteristics of children's behavior problems,and to study the influencing factors about children's behavior problems. Methods A total of 176 children aged from 7 to 11 were chosen from four primary schools in Nanchang,and their parents were asked to fill in the questionnaire and Conners Parent Symptom Questionnaire (PSQ).The concentrations of BPA in serum samples were measured by using ELISA,and the sex hormones levels of luteinizing hormone (LH),follicle stimulating hormone (FSH),estradiol (E2),testosterone (T) were detected by chemiluminoimmunoassay. Results The proprotion of children's behavior problems was 19.3%,among which psychosomastic disorder was the highest (6.8%).The prevalence of learning problem and hyperactivity impulse index in boys were higher significantly than that of girls prominently.The detection rate on behavior problems of children aged 8 years was the highest.The levels of serum BPA positively affected children's anxiety (β=0.172).After adjustment for potential confounders,potential protective factors might be high level of mother's education and E2 or T [OR mother's education=0.631;OR(E2 and T)=0.804]. Conclusions The detection rate of behavior problems among children in Nanchang is high.Measures like improving mother's education,reducing BPA exposure,and controlling the level of sex hormones decrease need to be taken to prevent child behavior problems.

Key words: behavior problem, bisphenol-A, sex hormone, children