关键词: 急性呼吸道感染, 病毒, 儿童

Abstract: Objective To understand the viral pathogen of children with acute respiratory infection(ARI) in Sanmenxia,and to provide guidance for direct clinical diagnosis and treatment. Methods Nasopharyngeal swabs were collected from 578 inpatient children diagnosed with ARI,and respiratory syncytial virus (RSV),adenovirus(ADV),parainfluenza virus Ⅰ,Ⅱ,Ⅲ (PIV Ⅰ～Ⅲ),influenza virus A,B (IVA,IVB) were detected by direct immunofluorescence. Results The total positive rate of virus pathogen of children with ARI was 61.59%.45.22% of the positive specimens were mixed infection.The total positive rate of virus pathogen was the highest in winter (77.35%) and the lowest in summer(25.0%).The total virus detection rate of lower respiratory tract infection was higher than that of upper respiratory tract infection.The detection rates of RSV,PIV Ⅲ and IVA ranked the top three,with 30.62%,28.89% and 21.97%,respectively.The detection rates of RSV and PIV Ⅲ were higher in lower respiratory tract infections in children under 3 years of age during the fall and winter.IVA had a higher detection rate in children with upper respiratory tract infection in winter. Conclusions RSV,PIV Ⅲ,IVA are main pathogens of acute respiratory tract infections in children from Sanmenxia area.RSV and PIV Ⅲ are the main pathogens of lower respiratory tract infections in children under 3 years old in autumn and winter.IVA is the main pathogen of upper respiratory tract infection in children of all ages in winter.It is of great significance to early diagnose virus pathogen and to avoid antibiotics abuse to detect viral pathogens in ARI children.

Key words: acute respiratory infection, virus, children