关键词: 早产儿, 铁, 贫血, 预防

Abstract: Objective To study the clinical efficacy of low dose iron supplementation on prevention of premature infant anemia. Methods A total of 68 premature infants were randomly selected as research objects from the follow-up center of high-risk infants in Nanjing Maternal and Child Health Hospital. The research group was treated with low dose of iron according to the feeding pattern of the premature infants. The breast-fed infants were supplied with oral elemental iron 2 mg/kg per day and the artificial feeding infants were supplied with oral elemental iron 1 mg/kg per day. The iron dosage of mixed-fed infants were chosen according to the proportion of formula of total milk amount(<50%,2 mg/kg;≥50%,1.5 mg/kg). Over the same period,another 72 premature infants who did not participate in follow up were chosen as control group without oral supplement of iron. The routine blood was tested when the premature infants were six months old. Results The average hemoglobin level of intervention group was higher than that of the control group (P<0.05) and the incidence of anemia in intervention group was significantly lower than that in control group (P<0.05). In addition,no significant differences on the incidence of anemia were found among infants with different feeding-pattern in intervention group. Conclusions Low dose iron supplementation based on feeding patterns can effectively improve the levels of iron storage and reduce the prevalence of anemia in premature infants.

Key words: premature infants, iron, anemia, prevention