改良婴幼儿孤独症量表中文简化版在3～4岁儿童中的应用分析

doi:10.11852/zgetbjzz2019-1709

中国儿童保健杂志 ›› 2020, Vol. 28 ›› Issue (5): 571-573.DOI: 10.11852/zgetbjzz2019-1709

改良婴幼儿孤独症量表中文简化版在3～4岁儿童中的应用分析

陈强¹, 袁滨², 徐文娟¹, 戚小兵¹, 杨丽勇³, 齐洋洋⁴

1 珠海市妇幼保健院,广东珠海 519001;
2 抚州市第三医院,江西抚州 344000;
3 珠海高新技术产业开发区金鼎社区卫生服务中心,广东珠海 519008;
4 珠海市香洲区五洲幼儿园,广东珠海 519000

收稿日期:2019-11-21 发布日期:2020-05-10 出版日期:2020-05-10
作者简介:陈强(1980-),男,四川人,副主任医师,硕士学位,主要研究方向为发育行为儿科学。
基金资助:
广东省医学科学技术研究基金(B2018141)

Application analysis of the Chinese simplified version of M-CHAT in children aged 3 to 4 years

CHEN Qiang¹, YUAN Bin², XU Wen-juan¹, QI Xiao-bing¹, YANG Li-yong³, QI Yang-yang⁴

1 Zhuhai Maternal and Child Health Hospital, Zhuhai, Guangdong 519001, China;
2 The Third Hospital of Fuzhou City, Fuzhou, Jiangxi 344000, China;
3 Jinding Community Health Service Center, Zhuhai High Tech Industrial Development Zone, Zhuhai, Guangdong 519008, China;
4 Wuzhou Kindergarten of Xiangzhou District, Zhuhai, Guangdong 519000, China

Received:2019-11-21 Online:2020-05-10 Published:2020-05-10

摘要/Abstract

摘要： 目的探索改良婴幼儿孤独症量表中文简化版(M-CHAT中文简化版)在3～4岁儿童中筛查孤独症谱系障碍(ASD)的应用价值,并制定合适界值。方法在2018年1—12月期间,选取年龄在3～4岁之间临床诊断为ASD儿童48例及正常发育儿童96名为研究对象,对其分别进行M-CHAT中文简化版评定,并绘制ROC曲线,以评价该量表在3～4岁儿童中筛查ASD的价值。结果 M-CHAT中文简化版在3～4岁儿童中筛查ASD时,其ROC曲线下面积AUC为0.94(95%CI:0.893～0.975);当筛查界限分为13分时,M-CHAT中文简化版区别ASD和非ASD能力最高,其灵敏度为0.94(95%CI:0.828～0.987)、特异度为0.82(95%CI:0.732～0.893)、Youden指数为0.76、阳性概率比5.29(95%CI:3.400～8.200)、阴性概率比0.08(95%CI:0.030～0.200)、阳性预测值为72.58%、阴性预测值为96.34%。结论 M-CHAT中文简化版筛查3～4岁ASD儿童能力较强,值得在3～4岁年龄段儿童ASD筛查工作中推广应用。

关键词: 孤独症, M-CHAT中文简化版, 儿童

Abstract: Objective To explore the application value of Chinese simplified version of M-CHAT to screen autism spectrum disorder (ASD) in children aged 3 to 4 years,and to establish appropriate thresholds. Methods A total of 48 ASD children aged 3 to 4 years and 96 normal developing children were selected as subjects from January 2018 to December 2018. The Chinese simplified version of M-CHAT was used and ROC curve was drawn to evaluate the value of the scale in screening ASD among children aged 3 to 4 years. Results Using the Chinese simplified version of M-CHAT in screening ASD in children aged 3 to 4 years old,the area under the curve(AUC) was 0. 94 (95%CI:0. 893―0. 975). When the cutoff point was divided into 13,the Chinese simplified version of M-CHAT showed the highest ability to distinguish ASD from non-ASD. Its sensitivity was 0. 94 (95% CI:0. 828―0. 987),specificity was 0. 82 (95% CI:0. 732―0. 893),Youden index was 0. 76,positive probability ratio was 5. 29 (95% CI:3. 400-8. 200) and negative probability ratio was 0. 08 (95% CI:0. 030―0. 200). The positive predictive value was 72. 58% and the negative predictive value was 96. 34%. Conclusion The Chinese simplified version of M-CHAT shows strong ability to screen ASD children aged 3 to 4 years,and is well worth popularizing and applying in ASD screening for children aged 3 to 4 years.

Key words: autism, Chinese simplified version of M-CHAT, children

中图分类号:

R749.91

陈强, 袁滨, 徐文娟, 戚小兵, 杨丽勇, 齐洋洋. 改良婴幼儿孤独症量表中文简化版在3～4岁儿童中的应用分析[J]. 中国儿童保健杂志, 2020, 28(5): 571-573.

CHEN Qiang, YUAN Bin, XU Wen-juan, QI Xiao-bing, YANG Li-yong, QI Yang-yang. Application analysis of the Chinese simplified version of M-CHAT in children aged 3 to 4 years[J]. journal1, 2020, 28(5): 571-573.

参考文献

[1] Sung M,Goh TJ,Tan B,et al.Comparison of DSM-Ⅳ-TR and DSM-5 criteria in diagnosing autism spectrum disorders in singapore[J].J Autism Dev Disord,2018,48(10):3273-3281.
[2] Doernberg E,Hollander E.Neurodevelopmental disorders (ASD and ADHD):DSM-5,ICD-10,and ICD-11[J].CNS Spectr,2016,21(4):295-299.
[3] 第二次全国残疾人抽样调查领导小组,中华人民共和国国家统计局.2006年第二次全国残疾人抽样调查主要数据公报[J].中国康复理论与实践,2006,12(12):1013.
[4] Barendse EM,Hendriks M,Thoonen G,et al.Social behaviour and social cognition in high-functioning adolescents with autism spectrum disorder (ASD):two sides of the same coin?[J].Cogn Process,2018,19(4):545-555.
[5] Wolstencroft J,Robinson L,Srinivasan R,et al.A systematic review of group social skills interventions,and meta-analysis of outcomes,for children with high functioning ASD[J].J Autism Dev Disord,2018,48(7):2293-2307.
[6] Cappe É,Poirier N,Sankey C,et al.Quality of life of French Canadian parents raising a child with autism spectrum disorder and effects of psychosocial factors[J].Qual Life Res,2018,27(4):955-967.
[7] Wang Y,Xiao L,Chen RS,et al.Social impairment of children with autism spectrum disorder affects parental quality of life in different ways[J].Psychiatry Res,2018,266:168-174.
[8] 姜凌霄,李改智,杜亚松.孤独谱系障碍筛查工具的比较分析[J].中国神经精神疾病杂志,2015,41(3):189-192.
[9] 龚郁杏,刘靖,郭延庆,等.改良婴幼儿孤独症量表中文简化版的效度和信度[J].中国心理卫生杂志,2015,29(2):121-124.
[10] Guo C,Luo M,Wang X,et al.Reliability and Validity of the Chinese Version of Modified Checklist for autism in toddlers,revised,with follow-up(M-CHAT-R/F)[J].J Autism Dev Disord,2019,49(1):185-196.
[11]Zwaigenbaum L,Penner M.Autism spectrum disorder:advances in diagnosis and evaluation[J].BMJ,2018,361:k1674.
[12]Hirota T,So R,Kim YS,et al.A systematic review of screening tools in non-young children and adults for autism spectrum disorder[J].Res Dev Disabil,2018,80:1-12.

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改良婴幼儿孤独症量表中文简化版在3～4岁儿童中的应用分析

Application analysis of the Chinese simplified version of M-CHAT in children aged 3 to 4 years

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