关键词: 癫痫, 睡眠障碍, 学龄前儿童

Abstract: Objective To analyze the sleep status of preschool children with epilepsy,and to explore the prevalence and influencing factors of the sleep problems. Methods From June 2018 to June 2019,a total of 96 children with epilepsy aged 3 to 5 in the Department of Pediatrics of the Second Affiliated Hospital of Xi'an Jiaotong University were selected as the epilepsy group,and 97 healthy children matched by age and gender were as controls. The Children's Sleep Habits Questionnaire (CSHQ) was used to investigate and analyze their sleep status,and the total score of CSHQ over 54 points was considered as poor sleep quality. Univariate analysis and Logistic regression analysis were used to determine the related factors that may lead to poor sleep quality in children with epilepsy. Results 1) The incidence of poor sleep quality in epilepsy group was higher than that in control group (33.33% vs. 10.20%,P＜0.001). 2) Univariate analysis showed that seizure types (χ²=7.200,P=0.007),seizure frequency (χ²=14.189,P=0.001) and the time periods of seizure(χ²=6.667,P =0.036)may relate to the occurrence of poor sleep quality. 3) Logistic regression analysis showed that generalized seizure (OR=4.996),seizures concentrated in the sleep period (OR=4.320),frequency≥4 times/month (OR=7.740) were risk factors for poor sleep quality in children with epilepsy. Conclusions Children with epilepsy have shorter sleep duration,and are more likely to have sleep problems than normal preschoolers. It is supposed to give early identification and intervention for epilepsy children with high-risk factors for poor sleep quality.

Key words: epilepsy, sleep disorders, preschool children